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伴有罕见心脏转移的肺泡软组织肉瘤:一例报告并文献复习

Alveolar Soft Part Sarcoma with Unusual Cardiac Metastasis: A Case Report and Review of the Literature.

作者信息

Tiwari Abhinav, Bangalore Bhavana Siddegowda, Sharma Himani, Ammari Zaid, Khan Mohammad S, Khan Zubair, Simo Hermann

机构信息

Department of Internal Medicine, University of Toledo Medical Center, 3000 Arlington Avenue, MS 1150, Toledo, OH 43614, USA.

Department of Cardiology, University of Toledo Medical Center, 3000 Arlington Avenue, MS 1150, Toledo, OH 43614, USA.

出版信息

Case Rep Cardiol. 2017;2017:7248727. doi: 10.1155/2017/7248727. Epub 2017 Aug 6.

DOI:10.1155/2017/7248727
PMID:28845314
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5563395/
Abstract

Alveolar soft part sarcoma is a very uncommon soft tissue malignancy which accounts for <1% of soft tissue sarcoma. It is a malignant and highly vascular tumor arising most commonly in the musculature of the lower extremities, with metastasis primarily to the lungs, bones, and brain. Cardiac metastasis is very rare and only 5 cases have been reported in the literature so far. We report a case of a young woman with a history of surgically resected alveolar soft part sarcoma of left thigh who presented with persistent dry cough and was found to have a cardiac mass, which on biopsy proved to be alveolar soft part sarcoma.

摘要

肺泡软组织肉瘤是一种非常罕见的软组织恶性肿瘤,占软组织肉瘤的比例不到1%。它是一种恶性且血管丰富的肿瘤,最常发生于下肢肌肉组织,主要转移至肺、骨和脑。心脏转移非常罕见,迄今为止文献中仅报道过5例。我们报告一例年轻女性病例,该患者有左大腿肺泡软组织肉瘤手术切除史,出现持续干咳,检查发现有心脏肿块,活检证实为肺泡软组织肉瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0d/5563395/af02b991ba08/CRIC2017-7248727.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0d/5563395/ea8cf64a9316/CRIC2017-7248727.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0d/5563395/8373fa3b71aa/CRIC2017-7248727.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0d/5563395/af02b991ba08/CRIC2017-7248727.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0d/5563395/ea8cf64a9316/CRIC2017-7248727.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0d/5563395/8373fa3b71aa/CRIC2017-7248727.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0d/5563395/af02b991ba08/CRIC2017-7248727.003.jpg

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本文引用的文献

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Alveolar soft-part sarcoma in the left forearm with cardiac metastasis: A case report and literature review.左前臂肺泡软组织肉瘤伴心脏转移:病例报告及文献复习
Oncol Lett. 2016 Jan;11(1):81-84. doi: 10.3892/ol.2015.3889. Epub 2015 Nov 6.
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Prominent Intracytoplasmic Crystals in Alveolar Soft Part Sarcoma (ASPS): An Aid in Cytological Diagnosis.肺泡软组织肉瘤(ASPS)中的显著胞浆内晶体:对细胞学诊断的辅助作用
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肺泡软组织肉瘤:19例患者的临床表现、治疗及预后
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Primary alveolar soft part sarcoma of the scapula.肩胛骨原发性肺泡软组织肉瘤
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Int J Cardiol. 2007 Jan 18;114(3):e93-5. doi: 10.1016/j.ijcard.2006.07.024. Epub 2006 Oct 18.
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Alveolar soft-part sarcoma: a cardiac metastasis as a rare site of relapse.肺泡软组织肉瘤:心脏转移作为一种罕见的复发部位。
Am J Clin Oncol. 2006 Aug;29(4):422-3. doi: 10.1097/01.coc.0000172283.52252.5e.
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A proposed explanation for female predominance in alveolar soft part sarcoma. Noninactivation of X; autosome translocation fusion gene?肺泡软组织肉瘤女性居多的一种推测性解释。X染色体未失活;常染色体易位融合基因?
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