Saenko V S, Kapsargin F P, Pesegov S V, M V
I.M. Sechenov First Moscow State Medical University of Minzdrav of Russia, Department of Urology, University Clinic of Urology 2, R.M. Fronshteyn Urology Clinic, Moscow, Russia.
Voino-Yasenetsky Krasnoyarsk State Medical University, Department of Urology, Andrology and Sexology, IPE, Krasnoyarsk, Russia.
Urologiia. 2017 Jul(3):16-21. doi: 10.18565/urol.2017.3.16-21.
Urinary tract infection (UTI) are a risk factor for diseases leading to impairment of renal function and kidney stone disease (KSD). Growing resistance of uropathogens to antibacterial agents is a challenging issue in most countries of the world. Urolithiasis is the second most prevalent urologic condition following urinary tract infections and has a pronounced tendency to recur. Rational stone metaphylaxis leads to a significant reduction in the incidence of recurrent stones. In recent decades, there has been a markedly increasing interest in plant-based therapies in managing urologic diseases.
To evaluate the effectiveness of phytotherapeutic medication Phytolysin in the integrated management of UTI and metaphylaxis of urolithiasis.
Comprehensive evaluation of the effectiveness of Phytolysin was conducted at the Department of Urology, I.M. Sechenov First MSMU and Department of Urology, Andrology and Sexology, Voino-Yasenetsky Krasnoyarsk SMU in 40 women with episodes of exacerbation of chronic cystitis and 30 patients of both sexes during the postoperative metaphylaxis of the KSD. The age of the patients ranged from 20 to 68 years (mean age 40+/-2,8 years).
Adding Phytolysin to the integrated management results in the improvement in general clinical signs and laboratory parameters of blood and urine, leads to a decrease in the level of leukocyturia, bacteriuria and an increase in diuresis and urinary alkalinization, reduces the number relapses of UTI and stone formation.
Phytolysin is an effective and safe medication.
尿路感染（UTI）是导致肾功能损害和肾结石病（KSD）的疾病的危险因素。在世界上大多数国家，尿路病原体对抗菌剂的耐药性不断增强是一个具有挑战性的问题。尿石症是仅次于尿路感染的第二常见泌尿系统疾病，且有明显的复发倾向。合理的结石预防性治疗可显著降低复发性结石的发生率。近几十年来，人们对植物疗法治疗泌尿系统疾病的兴趣明显增加。
评估植物疗法药物Phytolysin在尿路感染综合管理和尿石症预防性治疗中的有效性。
在莫斯科第一谢马什克国立医科大学泌尿外科以及克拉斯诺亚尔斯克沃伊诺-亚谢涅茨基国立医科大学泌尿外科、男科学与性学系，对40例慢性膀胱炎急性发作的女性患者和30例男女患者在肾结石病术后预防性治疗期间，对Phytolysin的有效性进行了综合评估。患者年龄在20至68岁之间（平均年龄40±2.8岁）。
在综合治疗中添加Phytolysin可改善血液和尿液的一般临床体征及实验室参数，降低白细胞尿、菌尿水平，增加尿量并使尿液碱化，减少尿路感染复发次数和结石形成。
Phytolysin是一种有效且安全的药物。
