Spivak L G, Enikeev D V, Platonova D V
I.M. Sechenov First MSMU of Minzdrav of Russia, Moscow, Russia.
Urologiia. 2017 Sep(4):32-36.
To evaluate the effectiveness of the herbal preparation Phytolysin in the comprehensive management of urate nephrolithiasis against the background of chronic cystitis exacerbation.
The study comprised 21 patients aged 19 to 57; 11 of them (the study group) received ciprofloxacin 500 mg once daily for 7 days, Phytolysin (for 1 month) and Blemaren (for 3 months), while 10 patients of control group were treated with antibacterial therapy and Blemaren. The clinical evaluation of the patients included laboratory testing and ultrasound imaging.
The combination therapy resulted in a decrease in leukocyturia and bacteriuria. There was no tendency to relapse. The occurrence of relapse was identified by dysuria, urgent and frequent urination, suprapubic pain and results of laboratory testing (leukocyturia, bacteriuria >103) on days 15, 29, 57, 85 and 112 of the study.
The findings suggest that the use of Phytolysin can be an effective and safe way to prevent exacerbation of chronic cystitis in patients with urate nephrolithiasis.
评估草药制剂Phytolysin在慢性膀胱炎急性发作背景下综合治疗尿酸盐肾结石的有效性。
该研究纳入了21名年龄在19至57岁之间的患者；其中11名（研究组）患者接受每日一次500毫克环丙沙星治疗7天，服用Phytolysin（为期1个月）和Blemaren（为期3个月），而对照组的10名患者接受抗菌治疗和Blemaren治疗。对患者的临床评估包括实验室检测和超声成像。
联合治疗使白细胞尿和菌尿减少。没有复发倾向。在研究的第15、29、57、85和112天，通过排尿困难、尿急、尿频、耻骨上疼痛以及实验室检测结果（白细胞尿、菌尿>103）来确定复发情况。
研究结果表明，使用Phytolysin可能是预防尿酸盐肾结石患者慢性膀胱炎急性发作的一种有效且安全的方法。
