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腹腔镜胆囊切除术相关胆管损伤的管理:三级中心经验

Management of Laparoscopic Cholecystectomy-Related Bile Duct Injuries: A Tertiary Center Experience.

作者信息

Kerimoglu Ramazan Saygin, Bostanci Erdal Birol, Dalgic Tahsin, Karaman Kerem, Kayapinar Ali Kemal, Ozer Ilter, Ulas Murat, Ozogul Yusuf Bayram, Akoglu Musa

机构信息

Turkiye Yuksek Ihtisas Teaching and Research Hospital, Department of Gastroenterological Surgery, Ankara, Turkey.

出版信息

Arch Iran Med. 2017 Aug;20(8):487-493.

Abstract

BACKGROUND

Laparoscopic cholecystectomy (LC)-related bile duct injuries remains a challenging issue with major implications for patient's outcome.

METHODS

Between January 2008 and December 2012, we retrospectively analyzed the management and treatment outcomes of 90 patients with bile duct injury following LC.

RESULTS

Forty-seven patients (52.2%) were treated surgically while the remaining 43 patients (47.8%) underwent non-surgical intervention. Injuries of Strasberg Type A and C were significantly more frequent in the non-surgical intervention group (P = 0.016, P = 0.044) whereas Type E2 was more frequent in the definitive surgery group (P < 0.001). The success rate of non-surgical intervention decreased as the waiting time increased whereas the success of definitive surgery was not time-dependent (P = 0.048). Initial jaundice (direct biluribin >1.3 gr/dL) significantly reduced the success rate of non-surgical interventions (P = 0.017). Presence of intraabdominal abscess significantly increased the complication rate after both definitive surgery and non-surgical interventions (P = 0.04, P = 0.023). Treatment success rates were similar in both surgery and non-surgical intervention groups according to the distribution of Strasberg injury types.

CONCLUSION

A multimodality approach is recommended in planning for patient-based treatment. Delayed referral reduces the success of nonsurgical interventions while it does not seem to significantly affect the success of surgical interventions when intraabdominal sepsis is under control.

摘要

背景

腹腔镜胆囊切除术(LC)相关的胆管损伤仍然是一个具有挑战性的问题,对患者的预后有重大影响。

方法

回顾性分析2008年1月至2012年12月期间90例LC术后胆管损伤患者的处理及治疗结果。

结果

47例(52.2%)患者接受了手术治疗,其余43例(47.8%)患者接受了非手术干预。非手术干预组中Strasberg A型和C型损伤明显更常见(P = 0.016,P = 0.044),而E2型在确定性手术组中更常见(P < 0.001)。非手术干预的成功率随着等待时间的增加而降低,而确定性手术的成功率与时间无关(P = 0.048)。初始黄疸(直接胆红素>1.3 gr/dL)显著降低了非手术干预的成功率(P = 0.017)。腹腔内脓肿的存在显著增加了确定性手术和非手术干预后的并发症发生率(P = 0.04,P = 0.023)。根据Strasberg损伤类型的分布,手术组和非手术干预组的治疗成功率相似。

结论

建议采用多模式方法进行基于患者的治疗规划。延迟转诊会降低非手术干预的成功率,而当腹腔内感染得到控制时,似乎不会显著影响手术干预的成功率。

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