Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
Department of Biostatistics, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
Med Sci Monit. 2017 Nov 4;23:5264-5270. doi: 10.12659/msm.907532.
BACKGROUND Major bile duct injury is the most worrisome complication of cholecystectomy. There is no detailed data about the incidence or treatment-related costs of bile duct injuries in Turkey. We aimed to determine prevalence and therapeutic costs of patients with major biliary duct injuries managed in our department, and further estimate a projection of these parameters at the national level. MATERIAL AND METHODS All patients admitted due to bile duct injury during cholecystectomy from 2011 to 2014 were included. Healthcare costs were calculated by summing of their all treatment-related costs in Istanbul Medical Faculty. We collected 2014-2015 data on number of patients diagnosed with cholecystitis in Turkey, the number of cholecystectomies, and the number of the interventions performed following these initial surgeries, which were obtained from the Turkish Social Security Institution. RESULTS Forty-nine patients were enrolled and bilioenteric diversion was performed in 39 patients: 20.4% of patients had Bismuth II, 38.8% had Bismuth III, and 40.8% had Bismuth IV biliary stricture. Comparison of stricture types with total costs, days of hospitalization, and outpatient clinic costs revealed significant differences. Mean total cost of corrective surgeries was 9199 TRY. We estimated that 1.5% to 2.4% of patients who underwent cholecystectomy in Turkey have bile duct injury (including 0.3% with major bile duct injury). CONCLUSIONS New preventive strategies should be used to avoid bile duct injuries, which have a huge financial impact on the national economy.
胆总管损伤是胆囊切除术最令人担忧的并发症。土耳其尚无胆管损伤发生率或治疗相关费用的详细数据。我们旨在确定我院收治的严重胆管损伤患者的患病率和治疗费用,并进一步估计这些参数在全国范围内的预测值。
所有因胆囊切除术导致胆管损伤而于 2011 年至 2014 年期间入院的患者均被纳入本研究。伊斯坦布尔医学系计算了患者所有治疗相关费用的总和,以此来计算医疗费用。我们收集了 2014-2015 年土耳其胆囊炎患者数量、胆囊切除术数量以及这些初始手术后进行的干预数量的数据,这些数据均来自土耳其社会保障机构。
共纳入 49 名患者,其中 39 名患者进行了胆肠分流术:20.4%的患者为毕氏 II 型胆管狭窄,38.8%为毕氏 III 型,40.8%为毕氏 IV 型胆管狭窄。比较狭窄类型与总费用、住院天数和门诊费用发现存在显著差异。矫正手术的平均总费用为 9199 土耳其里拉。我们估计,土耳其接受胆囊切除术的患者中有 1.5%至 2.4%(包括 0.3%的严重胆管损伤患者)发生胆管损伤。
应采用新的预防策略来避免胆管损伤,因为胆管损伤对国民经济具有巨大的经济影响。