Epstein L, Blumberg B, Crowley J, Samuel K, Goudsmit J, Cook S, Dowling P
Acta Neurol Scand. 1987 Apr;75(4):231-3. doi: 10.1111/j.1600-0404.1987.tb07925.x.
Serum HTLV-I antibodies were measured in 17 MS patients and 2 closely matched control groups by 2 different independent assays. A highly sensitive particle agglutination test was used to detect HTLV-I core protein antigens and an immunoblot assay with E. coli-expressed P21E transmembrane protein was employed to detect antibodies to HTLV-I evelope antigens. No serologic evidence of prior HTLV-I infection in our population of multiple sclerosis (MS) or Guillain-Barré Syndrome (GBS) patients was found.
通过两种不同的独立检测方法，对17例多发性硬化症患者和2个匹配良好的对照组进行血清HTLV-I抗体检测。采用高灵敏度颗粒凝集试验检测HTLV-I核心蛋白抗原，并用大肠杆菌表达的P21E跨膜蛋白免疫印迹试验检测HTLV-I包膜抗原抗体。在我们的多发性硬化症（MS）或吉兰-巴雷综合征（GBS）患者群体中，未发现既往HTLV-I感染的血清学证据。
