Search for HTLV-I and LAV/HTLV-III antibodies in serum and CSF of multiple sclerosis patients.

In order to confirm the findings on the presence of antibodies against human T-lymphotropic retroviruses in subjects affected by multiple sclerosis we studied paired serum and CSF samples from 32 MS patients. Both ELISA and Western blot procedures were employed to detect antibodies against HTLV-I and LAV/HTLV-III antigens. Negative results were obtained in all samples examined, except one which was reactive to HTLV-I in ELISA but not in Western blot.