Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
College of Animal Science and Technology, Qingdao Agricultural University, Qingdao, Shandong, China.
Antimicrob Agents Chemother. 2017 Oct 24;61(11). doi: 10.1128/AAC.01272-17. Print 2017 Nov.
Two adjacent colistin resistance gene variants, termed and -like, were identified in the chromosome of an isolate obtained from retail chicken meat. The variants showed 95.20% and 84.19% nucleotide sequence identity, respectively, to from porcine Functional cloning indicated that only conferred polymyxin resistance in both and The -like segment was also observed in other species, including , , and .
两种相邻的多粘菌素耐药基因变异体,分别称为 和 -样,在从零售鸡肉中获得的一株 分离株的染色体中被鉴定出来。这两种变异体与来自猪的 分别具有 95.20%和 84.19%的核苷酸序列同一性。功能克隆表明,只有 赋予了 和 对多粘菌素的耐药性。-样片段也存在于其他 种属中,包括 、 、和 。