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奥地利多发性硬化症的流行病学。

Epidemiology of Multiple Sclerosis in Austria.

机构信息

Clinic for Neurology 2, Med Campus III, Kepler University Clinic Linz, Linz, Austria.

出版信息

Neuroepidemiology. 2017;49(1-2):40-44. doi: 10.1159/000479696. Epub 2017 Aug 19.

DOI:10.1159/000479696
PMID:28848208
Abstract

BACKGROUND

To assess the incidence rate and prevalence ratio of multiple sclerosis (MS) in Austria.

METHODS

Hospital discharge diagnosis and MS-specific immunomodulatory treatment prescriptions from public health insurances, covering 98% of Austrian citizens with health insurance were used to extrapolate incidence and prevalence numbers based on the capture-recapture method.

RESULTS

A total of 1,392,629 medication prescriptions and 40,956 hospitalizations were extracted from 2 data sources, leading to a total of 13,205 patients. The incidence rate and prevalence ratio of MS in Austria based on the capture-recapture method were 19.5/100,000 person-years (95% CI 14.3-24.7) and 158.9/100,000 (95% CI 141.2-175.9), respectively. Female to male ratio was 1.6 for incidence and 2.2 for prevalence.

CONCLUSIONS

Incidence rates and prevalence ratios of MS in our study are within the upper range of comparable studies across many European countries as well as the United States.

摘要

背景

评估奥地利多发性硬化症 (MS) 的发病率和患病率比值。

方法

利用公共医疗保险的住院诊断和 MS 特异性免疫调节治疗处方(覆盖 98%的奥地利公民),基于捕获-再捕获方法推断发病率和患病率数据。

结果

从 2 个数据源中提取了 1392629 份药物处方和 40956 次住院治疗,共涉及 13205 名患者。基于捕获-再捕获方法,奥地利的 MS 发病率和患病率比值分别为 19.5/100000 人年(95%CI 14.3-24.7)和 158.9/100000(95%CI 141.2-175.9)。发病率的男女比例为 1.6,患病率的男女比例为 2.2。

结论

本研究中的 MS 发病率和患病率比值处于许多欧洲国家和美国类似研究的较高范围内。

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