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发达国家影响免疫功能低下个体的胃肠道寄生虫感染概述。

An overview of parasitic infections of the gastro-intestinal tract in developed countries affecting immunocompromised individuals.

作者信息

Siddiqui Zohaib A

机构信息

King's College London, St Thomas Street, London, SE1 9RT UK.

出版信息

J Parasit Dis. 2017 Sep;41(3):621-626. doi: 10.1007/s12639-017-0904-8. Epub 2017 Mar 11.

Abstract

In both developed and developing countries, parasitic infections continue to be a frequent cause of mortality and morbidity. Due to the globalization of the world, doctors must be fully prepared to deal with a plethora of parasitic infections. More commonly the gastrointestinal (GI) tract is infected and in developed countries protozoans are more likely to be the cause of infection compared to helminths. These GI protozoa are progressively becoming recognized as important pathogens in patients that are immunocompromised. The number of immunocompromised patients is increasing and therefore the likelihood of similar infections will also increase. This paper aims to highlight the key GI parasites affecting immunocompromised individuals in developed countries, discussing diagnosis, treatment options and also prevention. may be the most common GI parasite found in the immunocompromised host closely followed by Cyclospora, however, is the most common GI parasite found in developed countries. The pathogenesis of parasitic infection is not clear, poorly understood and diagnostic testing remains difficult with management continuing to be a challenge.

摘要

在发达国家和发展中国家,寄生虫感染仍然是导致死亡和发病的常见原因。由于世界全球化,医生必须做好充分准备,应对大量的寄生虫感染。更常见的是胃肠道受到感染,在发达国家,原生动物比蠕虫更有可能成为感染的原因。这些胃肠道原生动物逐渐被认为是免疫功能低下患者的重要病原体。免疫功能低下患者的数量在增加,因此类似感染的可能性也会增加。本文旨在强调影响发达国家免疫功能低下个体的关键胃肠道寄生虫,讨论诊断、治疗选择以及预防措施。 可能是免疫功能低下宿主中最常见的胃肠道寄生虫,其次是环孢子虫,然而, 是发达国家最常见的胃肠道寄生虫。寄生虫感染的发病机制尚不清楚,了解甚少,诊断测试仍然困难,管理仍然是一项挑战。

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