Homayouni Mohammad Mohsen, Behniafar Hamed, Mehbod Amir Sayed Ali, Mohammad-Sadeghi Mohammad-Javad, Maleki Bahman
Department of Parasitology and Mycology, School of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Department of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Parasit Dis. 2017 Sep;41(3):850-853. doi: 10.1007/s12639-017-0901-y. Epub 2017 Feb 28.
is an opportunistic organism that can cause extreme complications such as Pneumocystis pneumonia in immunocompromised individuals. There is no comprehensive study was conducted Iran to determine the prevalence of this infection in susceptible individuals. In the present study, 160 sera samples were collected from immunocompromised patients, including acquired immunodeficiency syndrome (AIDS) patients, diabetic patients, Hodgkin lymphoma patients and non-Hodgkin lymphoma patients. The specimens were collected from Imam Khomeini and army's 501 hospitals. The specimens were examined using indirect fluorescent antibody test. The results of the study showed that 39.30% specimens were found positive, with different rates in different groups, including 20, 22.50, 37.50, and 77.50% of diabetic patients, non-Hodgkin patients, Hodgkin lymphoma patients, and AIDS patients, respectively. This occurrence is relatively high and can be a potential life-threatening hazard to infected patients in studied groups, on the other hand the organism can be transmitted from infected people to other susceptible individuals.
是一种机会性生物体，可在免疫功能低下的个体中引发诸如肺孢子菌肺炎等极端并发症。伊朗尚未进行全面研究以确定这种感染在易感个体中的流行情况。在本研究中，从免疫功能低下的患者中收集了160份血清样本，包括获得性免疫缺陷综合征（艾滋病）患者、糖尿病患者、霍奇金淋巴瘤患者和非霍奇金淋巴瘤患者。样本取自伊玛目·霍梅尼医院和军队的501医院。使用间接荧光抗体试验对样本进行检测。研究结果显示，39.30%的样本呈阳性，不同组别的阳性率不同，糖尿病患者、非霍奇金患者、霍奇金淋巴瘤患者和艾滋病患者的阳性率分别为20%、22.50%、37.50%和77.50%。这种发生率相对较高，对研究组中的感染患者可能构成潜在的生命威胁，另一方面，该生物体可从感染者传播给其他易感个体。
