Pimentel-Nunes Pedro, Libânio Diogo, Dinis-Ribeiro Mário
Department of Gastroenterology, Portuguese Oncology Institute, Porto, Portugal.
Department of Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.
GE Port J Gastroenterol. 2017 Jan;24(1):8-21. doi: 10.1159/000450870. Epub 2016 Nov 1.
Gastric cancer is one of the most common and lethal cancers in the world. In Portugal, it is a major health problem presenting one of the highest incidence rates among European countries. In most Western countries, gastric cancer is generally diagnosed in advanced stages. Nevertheless, with the widespread use of upper endoscopy, gastric superficial neoplastic lesions are being increasingly recognized and diagnosed. However, there are no clear recommendations regarding who should be screened for its presence and only recently guidelines concerning the evaluation and management of these lesions were published. In this review, we summarize the current scientific evidence regarding diagnosis and management of gastric superficial neoplastic lesions. Topics like screening, diagnosis, endoscopic evaluation, management, treatment, pathologic evaluation and follow-up of patients with these lesions are covered and areas of future research are discussed. Whenever possible, evidence-based recommendations are made, and on the other cases expert opinion is presented.
胃癌是世界上最常见且致命的癌症之一。在葡萄牙，它是一个重大的健康问题，在欧洲国家中发病率位居前列。在大多数西方国家，胃癌通常在晚期才被诊断出来。然而，随着上消化道内镜检查的广泛应用，胃浅表性肿瘤性病变越来越多地被识别和诊断出来。但是，对于哪些人应该接受胃癌筛查并没有明确的建议，而且直到最近才发布了关于这些病变评估和管理的指南。在这篇综述中，我们总结了关于胃浅表性肿瘤性病变诊断和管理的当前科学证据。涵盖了这些病变患者的筛查、诊断、内镜评估、管理、治疗、病理评估和随访等主题，并讨论了未来研究的领域。只要有可能，我们就会给出基于证据的建议，在其他情况下则给出专家意见。
