Simmering Jacob E, Polgreen Linnea A, Comellas Alejandro P, Cavanaugh Joseph E, Polgreen Philip M
University of Iowa, Department of Pharmacy Practice and Science, Iowa City.
University of Iowa, Department of Internal Medicine, Iowa City.
Chronic Obstr Pulm Dis. 2016 Aug 29;3(4):729-738. doi: 10.15326/jcopdf.3.4.2016.0136.
Readmission within 30 days of a COPD hospitalization is a common measure of performance for COPD care. However, most studies of COPD readmission risk have been constrained to a single data source, private payer claims, or Medicare claims data, making it difficult to generalize results from these studies to other populations. The purpose of this study was to examine the risk for readmission within 30 days from time of discharge in patients with COPD using the Healthcare Cost and Utilization Project (HCUP) State Inpatient Database for California for the years 2005-2011. This statewide dataset allows us to consider all readmissions for COPD regardless of age or payer status. The total dataset included 28,265,070 visits among 17,918,374 patients over 480 hospitals. We identified patients with a hospitalization, a primary diagnosis related to COPD, age 40 or older, and discharged alive. We found 286,313 hospitalizations that matched this definition and included information on covariates such as comorbidities, age, and insurance status. To characterize the joint associations of these covariates with readmission within 30 days, we used a generalized linear model. Patients aged 40-64 are more likely to be readmitted to the hospital within 30 days of a COPD-related hospitalization than patients 65 and older. This effect persists after adjustment for patient severity, comorbidities, payer, and demographics. Our model featured an interaction of age with insurance type. We found that younger patients (aged 40-64) on public insurance have the highest readmission rates: 14.77% for Medicare and 16.27% for Medicaid. However, younger patients with private insurance have the lowest readmission rates at 8.25%. Additional significant covariates included whether or not the patient left against medical advice, and diagnoses of congestive heart failure and diabetes. In addition, we found that although admissions for COPD were highest in the winter, this is not true for COPD readmissions, which peak in summer. Also, inpatient mortality for patients admitted for COPD decreased from approximately 3% to 1.25% over the study period. Our results demonstrate that many of the risk factors for readmission may be dependent on the data source used. Furthermore, many of the strongest predictors are clearly related to the patients themselves. This observation may help explain why prior programs to reduce readmissions have had limited success.
慢性阻塞性肺疾病(COPD)住院后30天内再次入院是衡量COPD护理质量的一项常用指标。然而,大多数关于COPD再入院风险的研究都局限于单一数据源,如商业保险索赔数据或医疗保险索赔数据,这使得这些研究结果难以推广至其他人群。本研究旨在利用2005 - 2011年加利福尼亚州医疗成本与利用项目(HCUP)的州住院患者数据库,调查COPD患者出院后30天内再次入院的风险。这个全州范围的数据集使我们能够考虑所有COPD患者的再入院情况,而不论其年龄或付费者身份。整个数据集包括480多家医院中17918374名患者的28265070次就诊记录。我们确定了那些有过住院治疗、主要诊断与COPD相关、年龄在40岁及以上且出院时存活的患者。我们发现有286313次住院符合这一定义,并包含了诸如合并症、年龄和保险状况等协变量信息。为了描述这些协变量与30天内再入院之间的联合关联,我们使用了广义线性模型。40 - 64岁的患者在与COPD相关的住院治疗后30天内比65岁及以上的患者更有可能再次入院。在对患者病情严重程度、合并症、付费者和人口统计学因素进行调整后,这种影响仍然存在。我们的模型显示年龄与保险类型之间存在交互作用。我们发现,参加公共保险的年轻患者(年龄在40 - 64岁)再入院率最高:医疗保险患者为14.77%,医疗补助患者为16.27%。然而,参加商业保险的年轻患者再入院率最低,为8.25%。其他显著的协变量包括患者是否擅自离院、充血性心力衰竭和糖尿病的诊断。此外,我们发现虽然COPD住院人数在冬季最多,但COPD再入院情况并非如此,再入院高峰出现在夏季。而且,在研究期间,因COPD入院患者的住院死亡率从约3%降至1.25%。我们的研究结果表明,许多再入院风险因素可能取决于所使用的数据源。此外,许多最强的预测因素显然与患者自身有关。这一观察结果可能有助于解释为何先前减少再入院的项目成效有限。