针对双能X线吸收法，验证生物电阻抗分析法在评估5至18岁印度儿童身体成分中的应用

Validation of Bioelectric Impedance Analysis against Dual-energy X-Ray Absorptiometry for Assessment of Body Composition in Indian Children Aged 5 to 18 Years.

作者信息

Chiplonkar Shashi, Kajale Neha, Ekbote Veena, Mandlik Rubina, Parthasarathy Lavanya, Khadilkar Vaman, Khadilkar Anuradha

机构信息

Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India. Correspondence to: Dr Anuradha Khadilkar, Deputy Director, Hirabai Cowasji Jehangir Medical Research Institute, Old Building Basement, Jehangir Hospital, 32, Sassoon Road, Pune, Maharashtra 411 001, India.

出版信息

Indian Pediatr. 2017 Nov 15;54(11):919-924. doi: 10.1007/s13312-017-1182-3. Epub 2017 Aug 24.

DOI:10.1007/s13312-017-1182-3

PMID:28849765

Abstract

OBJECTIVE

To validate body composition measurements by Bioelectric Impedance Analysis (BIA) against Dual-Energy X-ray Absorptiometry (DXA) as the reference method in healthy children and adolescents.

DESIGN

Cross-sectional.

SETTING

Schools in and around Pune city, India.

PARTICIPANTS

A random sample of 210 (114 boys, 96 girls) apparently healthy Indian children and adolescents (5-18 y).

METHODS

Weight, height, Tanner stage (TS) were recorded. Body composition measures: fat-free mass (FFM), fat mass (FM), lean mass (LM), bone mineral content (BMC) and body fat percentage (%BF) were assessed by BIA and DXA on a single day. Agreement between the methods was estimated by Pearson's correlation, and Bland and Altman analysis.

MAIN OUTCOME MEASURES

%BF, FM, FFM, LM, BMC.

RESULTS

BIA underestimated %BF by 6.7 (3.7)% as compared to DXA. Mean FFM, BMC and LM by BIA were significantly higher than by DXA (P<0.001). These differences remained similar after adjusting for age, BMI and TS. Mean differences between FFM (-2.32 (1.39) kg), BMC (-0.18 (0.15) kg), and LM (-2.15 (1.34) kg) by DXA and BIA were significant (P<0.01). Correlations between BIA and DXA were 0.92 for %BF, 0.96 for LM and 0.98 for FFM and BMC. Both the methods were similar in identifying normal and overfat children as per their respective cut-offs.

CONCLUSION

BIA and DXA techniques are not interchangeable for assessment of body composition. However, BIA may be used in the field/clinical setting preferably with ethnicity specific references.

摘要

目的

验证在健康儿童和青少年中，以双能X线吸收法（DXA）作为参考方法时，生物电阻抗分析（BIA）测量身体成分的准确性。

设计

横断面研究。

地点

印度浦那市及其周边的学校。

参与者

随机抽取210名（114名男孩，96名女孩）明显健康的印度儿童和青少年（5 - 18岁）。

方法

记录体重、身高、坦纳分期（TS）。在同一天通过BIA和DXA评估身体成分指标：去脂体重（FFM）、脂肪量（FM）、瘦体重（LM）、骨矿物质含量（BMC）和体脂百分比（%BF）。通过Pearson相关性分析以及Bland和Altman分析评估两种方法之间的一致性。

主要观察指标

%BF、FM、FFM、LM、BMC。

结果

与DXA相比，BIA低估%BF 6.7（3.7）%。BIA测得的平均FFM、BMC和LM显著高于DXA（P<0.001）。在调整年龄、BMI和TS后，这些差异仍然相似。DXA和BIA测得的FFM（-2.32（1.39）kg）、BMC（-0.18（0.15）kg）和LM（-2.15（1.34）kg）之间的平均差异显著（P<0.01）。BIA与DXA之间的相关性为：%BF为0.92，LM为0.96，FFM和BMC为0.98。根据各自的临界值，两种方法在识别正常和超重儿童方面相似。