Suppr超能文献

可能提示节段性椎间盘源性疼痛的症状和体征。一项长达18年随访的融合研究。

Symptoms and signs possibly indicating segmental, discogenic pain. A fusion study with 18 years of follow-up.

作者信息

Nyström Bo, Weber Henrik, Schillberg Birgitta, Taube Adam

机构信息

Clinic of Spinal Surgery, Löt, SE-64594 Strängnäs, Sweden.

Department of Neurology, Ullevål Hospital, Oslo, Norway.

出版信息

Scand J Pain. 2017 Jul;16:213-220. doi: 10.1016/j.sjpain.2016.10.007. Epub 2016 Nov 21.

Abstract

BACKGROUND

Only two out of the five existing randomized studies have reported better results from fusion surgery for chronic low back pain (CLBP) compared to conservative treatment. In these studies the back symptoms of the patients were described simply as "chronic low back pain". One possible reason for the modest results of surgery is the lack of a description of specified symptoms that might be related to a painful segment/disc, and patient selection may therefore be more or less a matter of chance. Previous prospective studies including facet joint injections and discography and eventually MRI have failed to identify patients with a painful segment/disc that will benefit from fusion surgery.

PURPOSE

Our purpose was to analyse in detail the pre-operative symptoms and signs presented by patients who showed substantial relief from their back pain following spinal fusion surgery with the aim of possibly finding a pain pattern indicating segmental, discogenic pain.

METHODS

We analysed 40 consecutive patients, mean age 41 years, with a history of disabling low back pain for a mean of 7.7 years. Before surgery the patients completed a detailed questionnaire concerning various aspects of their back pain, and findings at clinical examination were thoroughly noted. Monosegmental posterior lumbar interbody fusion without internal fixation was performed using microsurgical technique. Outcome was assessed at 1, 2 and 4 years after surgery and finally at 18 years, using self-reporting measures and assessment by an independent examiner. Assessment at 18 years applied the Balanced Inventory for Spinal Disorders Questionnaire and the Roland-Morris Disability Questionnaire.

RESULTS

According to the independent observer's assessment at two years 27 of the 40 patients were much improved. Analysis of the pre-operative depiction of the back symptoms of this group revealed a rather uniform pattern, the most important being: dominating back pain originating in the midline of the spine, with a dull, aching character and stabbing pain in the same area provoked by sudden movements. Most patients in this group also had diffuse pain radiation of various extension down one or both legs and often bladder dysfunction with frequency. At clinical examination, localized interspinal tenderness was observed within the spinal area in question and the patient's back pain was provoked by pressure in that area and by tapping a neighbouring spinous process. At 18 years after surgery 19 patients assessed themselves as much improved. At that time 5 of them had pension due to age, 7 early pension, one worked full time and six patients part time. Eleven patients were re-operated due to defect bony healing.

CONCLUSIONS

The results may suggest that the use of a detailed symptom analysis and clinical examination may make it possible to select a subgroup of patients within the CLBP group likely to have better outcome following fusion surgery.

IMPLICATIONS

The next step would be to execute prospective studies and if our findings concerning back pain details and signs among CLPB patients can be confirmed this can provide for more accurate selection of patients suitable for fusion surgery.

摘要

背景

在现有的五项随机研究中,只有两项报告称,与保守治疗相比,融合手术治疗慢性下腰痛(CLBP)的效果更好。在这些研究中,患者的背部症状被简单描述为“慢性下腰痛”。手术效果一般的一个可能原因是缺乏对可能与疼痛节段/椎间盘相关的特定症状的描述,因此患者选择或多或少具有偶然性。先前包括小关节注射、椎间盘造影以及最终的磁共振成像(MRI)在内的前瞻性研究未能识别出能从融合手术中获益的疼痛节段/椎间盘患者。

目的

我们的目的是详细分析在接受脊柱融合手术后背痛得到显著缓解的患者术前出现的症状和体征,以期找到一种表明节段性、椎间盘源性疼痛的疼痛模式。

方法

我们分析了40例连续患者,平均年龄41岁,有导致残疾的下腰痛病史,平均时长7.7年。手术前,患者完成了一份关于其背痛各方面的详细问卷,并详细记录了临床检查结果。采用显微外科技术进行了无内固定的单节段腰椎后路椎间融合术。在术后1年、2年和4年以及最终在18年时使用自我报告措施和由独立检查者进行评估来评估结果。18年时的评估采用脊柱疾病平衡量表问卷和罗兰 - 莫里斯残疾问卷。

结果

根据独立观察者在两年时的评估,40例患者中有27例有明显改善。对该组患者术前背部症状描述的分析显示出一种相当一致的模式,最重要的是:以脊柱中线为起源的占主导地位的背痛,呈钝痛、酸痛性质,且同一区域因突然动作引发刺痛。该组中的大多数患者还伴有不同程度的沿一条或两条腿的弥漫性疼痛放射,且常伴有尿频的膀胱功能障碍。在临床检查中,在所讨论的脊柱区域内观察到局限性棘突间压痛,并且该区域受压以及轻敲相邻棘突会引发患者的背痛。术后18年,19例患者自我评估有明显改善。那时他们中有5人因年龄原因领取养老金,7人提前领取养老金,1人全职工作,6人兼职工作。11例患者因骨愈合缺陷而再次手术。

结论

结果可能表明,使用详细的症状分析和临床检查可能使在CLBP组中选择一个可能在融合手术后有更好结果的患者亚组成为可能。

启示

下一步将进行前瞻性研究,如果我们关于CLPB患者背痛细节和体征的发现能够得到证实,这可以为更准确地选择适合融合手术的患者提供依据。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验