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A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity.

作者信息

Kuepfer Lars, Clayton Olivia, Thiel Christoph, Cordes Henrik, Nudischer Ramona, Blank Lars M, Baier Vanessa, Heymans Stephane, Caiment Florian, Roth Adrian, Fluri David A, Kelm Jens M, Castell José, Selevsek Nathalie, Schlapbach Ralph, Keun Hector, Hynes James, Sarkans Ugis, Gmuender Hans, Herwig Ralf, Niederer Steven, Schuchhardt Johannes, Segall Matthew, Kleinjans Jos

机构信息

Institute of Applied Microbiology, RWTH, Aachen, Germany.

Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.

出版信息

Arch Toxicol. 2018 Jan;92(1):553-555. doi: 10.1007/s00204-017-2041-7. Epub 2017 Aug 29.

DOI:10.1007/s00204-017-2041-7
PMID:28852801
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5773653/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bca0/5773653/f91f3a9e57d2/204_2017_2041_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bca0/5773653/f91f3a9e57d2/204_2017_2041_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bca0/5773653/f91f3a9e57d2/204_2017_2041_Fig1_HTML.jpg

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