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Laparoscopic Roux-en-Y gastric bypass in adolescents with severe obesity (AMOS): a prospective, 5-year, Swedish nationwide study.腹腔镜 Roux-en-Y 胃旁路手术治疗青少年严重肥胖症(AMOS):一项前瞻性、5 年、瑞典全国性研究。
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Open Roux-en-Y gastric bypass in 925 patients without mortality.925例患者接受开放性Roux-en-Y胃旁路手术,无死亡病例。
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The Association of Demographic Characteristics with the Rate of Weight Loss and Changes in Nutritional Factors (Albumin, Vitamin D3, Ferritin) One Year after One Anastomosis Gastric Bypass.单吻合口胃旁路术后一年人口统计学特征与体重减轻率及营养因素(白蛋白、维生素D3、铁蛋白)变化的相关性
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European guideline on obesity care in patients with gastrointestinal and liver diseases - Joint European Society for Clinical Nutrition and Metabolism / United European Gastroenterology guideline.欧洲胃肠道和肝脏疾病患者肥胖管理指南- 临床营养和代谢学会与欧洲联合胃肠病学会指南。
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本文引用的文献

1
Bariatric surgery in older adults: Should there be an age limit?老年患者的减重手术:是否应该设置年龄限制?
Medicine (Baltimore). 2019 Jan;98(3):e13824. doi: 10.1097/MD.0000000000013824.
2
Missed Opportunities for Screening and Surveillance of Barrett's Esophagus in Veterans with Esophageal Adenocarcinoma.食管腺癌退伍军人中 Barrett 食管筛查和监测的错失机会。
Dig Dis Sci. 2019 Feb;64(2):367-372. doi: 10.1007/s10620-018-5336-5. Epub 2018 Oct 28.
3
Esophageal adenocarcinoma in Barrett's esophagus after sleeve gastrectomy: Case report and literature review.袖状胃切除术后巴雷特食管中的食管腺癌:病例报告及文献综述
Int J Surg Case Rep. 2018;52:132-136. doi: 10.1016/j.ijscr.2018.10.015. Epub 2018 Oct 12.
4
Medium to long-term outcomes of bariatric surgery in older adults with super obesity.超级肥胖老年人行减重手术后的中远期疗效。
Surg Obes Relat Dis. 2018 Apr;14(4):470-476. doi: 10.1016/j.soard.2017.11.008. Epub 2017 Nov 10.
5
Increased Metabolic Benefit for Obese, Elderly Patients Undergoing Roux-en-Y Gastric Bypass vs Sleeve Gastrectomy.与袖状胃切除术相比,接受Roux-en-Y胃旁路手术的肥胖老年患者代谢获益增加。
Obes Surg. 2018 Mar;28(3):636-642. doi: 10.1007/s11695-017-2904-2.
6
Reflux, Sleeve Dilation, and Barrett's Esophagus after Laparoscopic Sleeve Gastrectomy: Long-Term Follow-Up.腹腔镜袖状胃切除术后的胃食管反流、袖状扩张及巴雷特食管:长期随访
Obes Surg. 2017 Dec;27(12):3092-3101. doi: 10.1007/s11695-017-2748-9.
7
Trends in utilization of bariatric surgery, 2010-2014: sleeve gastrectomy dominates.2010 - 2014年减重手术的使用趋势:袖状胃切除术占主导地位。
Surg Obes Relat Dis. 2017 May;13(5):774-778. doi: 10.1016/j.soard.2017.01.031. Epub 2017 Jan 25.
8
Bariatric Surgery versus Intensive Medical Therapy for Diabetes - 5-Year Outcomes.减肥手术与强化药物治疗糖尿病——5年结果
N Engl J Med. 2017 Feb 16;376(7):641-651. doi: 10.1056/NEJMoa1600869.
9
Gastroesophageal reflux disease and Barrett's esophagus after laparoscopic sleeve gastrectomy: a possible, underestimated long-term complication.腹腔镜袖状胃切除术后的胃食管反流病和巴雷特食管:一种可能被低估的远期并发症。
Surg Obes Relat Dis. 2017 Apr;13(4):568-574. doi: 10.1016/j.soard.2016.11.029. Epub 2016 Dec 9.
10
Bariatric Surgery and Long-term Durability of Weight Loss.减肥手术与体重减轻的长期持久性
JAMA Surg. 2016 Nov 1;151(11):1046-1055. doi: 10.1001/jamasurg.2016.2317.

Roux-en-Y 胃旁路手术是一种安全有效的选择,可以改善老年退伍军人肥胖相关的主要合并症。

Roux-en-Y gastric bypass is a safe and effective option that improves major Co-Morbidities associated with obesity in an older, veteran population.

机构信息

University of California San Francisco Department of Surgery and the San Francisco Veterans Affairs Health Care System, 513 Parnassus Avenue, S321, San Francisco, CA, 94143-0470, USA.

University of California San Francisco Department of Medicine and the San Francisco Veterans Affairs Health Care System, 4150 Clement Street, San Francisco, CA, 94121, USA.

出版信息

Am J Surg. 2019 Oct;218(4):684-688. doi: 10.1016/j.amjsurg.2019.07.027. Epub 2019 Jul 20.

DOI:10.1016/j.amjsurg.2019.07.027
PMID:31399194
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6996506/
Abstract

BACKGROUND

Though over one-third of veterans suffer from obesity and its associated comorbidities, bariatric surgery (deleted: is seldom offered) is less commonly offered than in other populations.

METHODS

We reviewed surgical outcomes using CPRS/Vista data of ("deleted 308) 315 Roux-en-Y gastric bypass (RYGB) cases performed at a major VA Medical Center (1995-2017).

RESULTS

Patients were 69% male, with an average age 52 (65% over 50), and were followed for an average of 8 years; 158 (51%) underwent laparoscopic surgery, and the remaining open. Outcomes were: 30-day mortality- Open: 1.3%, Lap: 0%; anatomic leak-open: 0.3%, Lap: 0%. A total of 32 (10%) Clavien-Dindo ≥3 complications occurred. At 5 and 15 years, average BMI decreased from 47 preoperatively to 33.3 and 31 respectively, while excess body weight loss was 68%, and 80%, respectively. Co-morbidity resolution rates were between 70 and 80% diabetes, sleep apnea, hyperlipidemia, GERD, (delete - hypertension), and NASH.

CONCLUSIONS

RYGB offers sustained, long-term weight loss with significant resolution of major comorbidities in older veterans, with acceptably low morbidity and mortality.

摘要

背景

尽管超过三分之一的退伍军人患有肥胖症及其相关合并症,但与其他人群相比,很少为他们提供减重手术。

方法

我们使用 CPRS/Vista 数据回顾了在一家大型退伍军人事务医疗中心(1995-2017 年)进行的 315 例 Roux-en-Y 胃旁路术(RYGB)的手术结果。

结果

患者中男性占 69%,平均年龄为 52 岁(65%超过 50 岁),平均随访 8 年;158 例(51%)接受了腹腔镜手术,其余为开放性手术。结果如下:30 天死亡率-开放性:1.3%,腹腔镜:0%;解剖性漏-开放性:0.3%,腹腔镜:0%。共有 32 例(10%)发生了 Clavien-Dindo ≥3 级并发症。在 5 年和 15 年时,平均 BMI 从术前的 47 降至 33.3 和 31,而超重体重减轻分别为 68%和 80%。糖尿病、睡眠呼吸暂停、高脂血症、GERD(删除-高血压)和 NASH 的合并症缓解率在 70%至 80%之间。

结论

RYGB 为老年退伍军人提供了持续的、长期的体重减轻,并显著缓解了主要合并症,发病率和死亡率均较低。