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自体富血小板血浆联合剥脱性二氧化碳点阵激光治疗痤疮瘢痕的评估

Evaluation of autologous platelet-rich plasma plus ablative carbon dioxide fractional laser in the treatment of acne scars.

作者信息

Abdel Aal Ahmed Mohammed, Ibrahim Ibrahim Maeraj, Sami Nevein Ahmed, Abdel Kareem Ibrahim Mohammed

机构信息

a Department of Dermatology and Venerology (Laser Unit), Al-Hussein Hospital, Faculty of Medicine , Al- Azhar University , Cairo , Egypt.

b National Institute of Laser Enhanced Sciences , Cairo University , Egypt.

出版信息

J Cosmet Laser Ther. 2018 Apr;20(2):106-113. doi: 10.1080/14764172.2017.1368667. Epub 2017 Aug 30.

DOI:10.1080/14764172.2017.1368667
PMID:28853968
Abstract

INTRODUCTION

Acne scar is a common distressing complication of acne vulgaris. CO laser resurfacing proved effective for the treatment of this problem, but the associated complications may limit its use. Platelet-rich plasma (PRP) may increase the chance of favorable outcome.

AIM OF THE WORK

To evaluate the synergistic effects of autologous PRP with fractional CO laser resurfacing in the treatment of acne scars among Egyptian patients.

PATIENTS AND METHOD

This study included 30 patients suffering from post-acne scars. CO laser treatment was applied to both sides of the face followed by PRP injection for the right side. Evaluation was carried out through operating physicians, two blinded physicians as well as through patient's satisfaction.

RESULT

The right side of the face (PRP-treated side) achieved excellent improvement in 13.3% of the patients, while there was no excellent improvement on the left side.

CONCLUSION

Combination of fractional CO laser resurfacing and intradermal PRP was superior to CO laser alone for acne scar treatment.

摘要

引言

痤疮瘢痕是寻常痤疮常见的令人苦恼的并发症。二氧化碳激光磨皮术被证明对治疗这一问题有效,但相关并发症可能会限制其应用。富血小板血浆(PRP)可能会增加取得良好效果的机会。

研究目的

评估自体PRP与分次二氧化碳激光磨皮术联合治疗埃及患者痤疮瘢痕的协同效果。

患者与方法

本研究纳入30例痤疮后瘢痕患者。对双侧面部进行二氧化碳激光治疗,右侧随后注射PRP。通过手术医生、两名不知情的医生以及患者满意度进行评估。

结果

面部右侧(PRP治疗侧)13.3%的患者取得了极佳改善,而左侧未出现极佳改善情况。

结论

分次二氧化碳激光磨皮术联合皮内注射PRP治疗痤疮瘢痕优于单纯二氧化碳激光治疗。

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