White Christopher, Brahs Allyson, Dorton David, Witfill Kristin
Dr. White is with Dermatology Partners in Strongsville, Ohio.
Drs. Brahs, Dorton, and Witfill are with the Department of Dermatology, HCA Healthcare/USF Morsani College of Medicine, Largo Medical Center, in Largo, Florida.
J Clin Aesthet Dermatol. 2021 Nov;14(11):44-57.
Platelet-rich plasma (PRP) has been integrated into numerous treatment regimens for medical and aesthetic dermatology. While some of these approaches are well-established, many uses are underreported in the literature. We sought to identify and summarize the emerging dermatologic applications for PRP by conducting a comprehensive PubMed search of studies published between 2000 and 2020. These studies were reviewed to synthesize collection methods, treatment schedule, adverse effects, and the impact of therapy for new and emerging uses for PRP. In general, we identified positive treatment outcomes for skin rejuvenation, scar revision, alopecia, pigmentary disorders, lichen sclerosus, leprosy-induced peripheral neuropathy, plaque psoriasis, and nail disorders. Widely, therapy was well-tolerated and suitable for all reported phototypes. The variations in collection and application sequences make concrete recommendations difficult to discern, underscoring the need for a standardized approach to preparation and treatment methods. We hope this review serves as an outline for new and interesting uses for PRP and will help readers familiarize themselves with this exciting technology for comfortable integration into their practices.
富含血小板血浆（PRP）已被纳入众多医学和美容皮肤科的治疗方案中。虽然其中一些方法已得到充分确立，但许多应用在文献中报道较少。我们通过对2000年至2020年间发表的研究进行全面的PubMed检索，试图识别和总结PRP在皮肤科的新兴应用。对这些研究进行了综述，以综合PRP新的和新兴应用的采集方法、治疗方案、不良反应及治疗效果。总体而言，我们确定PRP在皮肤年轻化、瘢痕修复、脱发、色素沉着紊乱、硬化性苔藓、麻风引起的周围神经病变、斑块状银屑病和指甲疾病的治疗中取得了积极效果。广泛来说，该疗法耐受性良好，适用于所有报道的光类型。采集和应用顺序的差异使得难以辨别具体的推荐方案，这突出了对制备和治疗方法采用标准化方法的必要性。我们希望这篇综述能为PRP的新的和有趣的应用提供一个概述，并帮助读者熟悉这项令人兴奋的技术，以便将其顺利融入他们的实践中。
