Farhood Bagher, Bahreyni Toossi Mohammad Taghi, Soleymanifard Shokouhozaman, Mortezazadeh Tohid
Medical Physics and Medical Engineering Department, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Medical Physics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Contemp Oncol (Pozn). 2017;21(3):232-239. doi: 10.5114/wo.2017.70114. Epub 2017 Sep 29.
Our objective was to quantify the accuracy of dose calculation in the build-up region of the tangential field of the breast for a TiGRT treatment planning system (TPS).
Thermoluminescent dosimeter (TLD) chips were arranged in a RANDO phantom for the dose measurement. TiGRT TPS was also used for the dose calculation. Finally, confidence limit values were obtained to quantify the accuracy of the dose calculation of the TPS at the build-up region.
In the open field, for gantry angles of 15°, 30°, and 60°, the confidence limit values were 17.68, 19.97, and 34.62 at a depth of 5 mm, and 24.01, 19.07, and 15.74 at a depth of 15 mm, respectively. In the wedge field, for gantry angles of 15°, 30°, and 60°, the confidence limit values were 21.64, 26.80, and 34.87 at a depth of 5 mm, and 27.92, 22.04, and 20.03 at a depth of 15 mm, respectively. Additionally, the findings showed that at a depth of 5 mm, the confidence limit values increased with increasing gantry angle while at a depth of 15 mm, the confidence limit values decreased with increasing gantry angle.
Overall, TiGRT TPS overestimated doses compared to TLD measurements, and the confidence limit values were greater for the wedge field than for the open fields. Our findings suggest that the assessment of dose distributions in large-dose gradient regions (i.e. build-up region) should not entirely rely on TPS calculations.
我们的目标是量化用于TiGRT治疗计划系统(TPS)的乳腺切线野建成区剂量计算的准确性。
将热释光剂量计(TLD)芯片布置在RANDO体模中进行剂量测量。TiGRT TPS也用于剂量计算。最后,获得置信限值以量化TPS在建成区剂量计算的准确性。
在开放野中,对于15°、30°和60°的机架角度,在5 mm深度处的置信限值分别为17.68、19.97和34.62,在15 mm深度处分别为24.01、19.07和15.74。在楔形野中,对于15°、30°和60°的机架角度,在5 mm深度处的置信限值分别为21.64、26.80和34.87,在15 mm深度处分别为27.92、22.04和20.03。此外,研究结果表明,在5 mm深度处,置信限值随机架角度增加而增加,而在15 mm深度处,置信限值随机架角度增加而降低。
总体而言,与TLD测量相比,TiGRT TPS高估了剂量,并且楔形野的置信限值大于开放野。我们的研究结果表明,在大剂量梯度区域(即建成区)评估剂量分布不应完全依赖于TPS计算。