Division of Neurology, Department of Internal Medicine, King Saud University, PO Box 7805, Riyadh, 11472, Saudi Arabia.
Department of Internal Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Muscle Nerve. 2018 Apr;57(4):581-585. doi: 10.1002/mus.25948. Epub 2017 Sep 13.
We sought to translate, culturally adapt, and assess the Arabic version of the 15-item myasthenia gravis quality-of-life revised scale (MGQOL15R).
We assessed reliability with Cronbach α; reproducibility with intraclass correlation coefficient (ICC); validity with Spearman correlations for myasthenia gravis (MG)-specific activities of daily living (MG-ADL), MG composite (MGC) score, and MG manual muscle test (MG-MMT) and with MGQOL15R in patients with different disease severity through the Kruskal-Wallis test; and sensitivity to change with Wilcoxon signed-rank test.
In 65 enrolled patients, the mean MGQOL15R score was 10.84 ± 8.11 (α = 0.94, ICC = 0.95). The correlation coefficients between MGQOL15R and MGC, MG-ADL, and MG-MMT scores were 0.75, 0.75, and 0.74, respectively (P < 0.001). MGQOL15R scores were significantly higher (worse) in patients with more severe disease at baseline and significantly lower (better) in improved patients at follow-up.
The Arabic version of MGQOL15R is valid, reliable, stable, and sensitive to changes. Muscle Nerve 57: 581-585, 2018.
我们旨在翻译、文化调适并评估 15 项重症肌无力生活质量修订量表（MGQOL15R）的阿拉伯文版本。
我们通过克朗巴赫 α评估信度；通过内类相关系数（ICC）评估重现性；通过Spearman 相关性评估有效性，评估对象为重症肌无力（MG）特定日常生活活动（MG-ADL）、MG 综合评分（MGC）和 MG 手动肌肉测试（MG-MMT）与重症肌无力患者不同疾病严重程度的 MGQOL15R，通过 Kruskal-Wallis 检验评估；通过 Wilcoxon 符号秩检验评估敏感性。
在纳入的 65 名患者中，MGQOL15R 的平均得分是 10.84±8.11（α=0.94，ICC=0.95）。MGQOL15R 与 MGC、MG-ADL 和 MG-MMT 评分之间的相关系数分别为 0.75、0.75 和 0.74（P＜0.001）。基线时疾病严重程度较高的患者的 MGQOL15R 评分显著较高（较差），随访时病情改善的患者的 MGQOL15R 评分显著较低（较好）。
MGQOL15R 的阿拉伯文版本是有效、可靠、稳定且能敏感反映变化的。神经肌肉疾病 57:581-585,2018.
