Department of Neurology, West China Hospital of Sichuan University, Chengdu, China.
West China School of Public Health, Sichuan University, Chengdu, China.
Muscle Nerve. 2019 Jan;59(1):95-99. doi: 10.1002/mus.26313. Epub 2018 Nov 28.
We sought to translate, cross-culturally adapt, and evaluate the internal consistency and validity of the Chinese version of the 15-Item Myasthenia Gravis Quality of Life (MG-QOL15).
Translation and cross-cultural adaptation of the MG-QOL15 were performed. We used Cronbach's α to test internal consistency, one-way analysis of variance to test construct validity, and Pearson or Spearman correlations to test discriminant and concurrent validity.
We enrolled 168 outpatients. Internal consistency was excellent (Cronbach's α = 0.928). The MG-QOL15 discriminated MG severity as stratified by the MG Composite (MGC; P < 0.001) and Osserman class (P = 0.01). Concurrent validity was low to moderate with the subscales of the 36-item Short Form (-0.31 to ∼-0.59), MGC (r = 0.46), and Myasthenia Gravis Activities of Daily Living profile (r = 0.54).
The Chinese MG-QOL15 showed comparable construct, discriminant and concurrent validity, and internal consistency with to the original version. Muscle Nerve 59:95-99, 2019.
我们旨在翻译、跨文化调适并评估 15 项重症肌无力生活质量量表（MG-QOL15）中文版的内部一致性和有效性。
对 MG-QOL15 进行翻译和跨文化调适。我们使用克朗巴赫 α 检验内部一致性，单因素方差分析检验结构有效性，皮尔逊或斯皮尔曼相关检验判别和同时效度。
我们纳入了 168 名门诊患者。内部一致性极好（克朗巴赫 α=0.928）。MG-QOL15 区分了 MG 严重程度，按 MG 综合评分（MGC；P<0.001）和 Osserman 分级（P=0.01）分层。与 36 项简短表单的子量表（-0.31 到-0.59）、MGC（r=0.46）和重症肌无力日常生活活动量表（r=0.54）的同时效度为低到中度。
中文版 MG-QOL15 与原始版本具有可比的结构、判别和同时效度以及内部一致性。神经肌肉疾病 59:95-99, 2019。
