Clinical Psychology Unit, Department of Psychology, University of Sheffield.
Primary Care Psychological Therapies Service, Greater Manchester West Mental Health NHS Foundation Trust.
J Consult Clin Psychol. 2017 Sep;85(9):835-853. doi: 10.1037/ccp0000231.
Some cases are thought to be more complex and difficult to treat, although there is little consensus on how to define complexity in psychological care. This study proposes an actuarial, data-driven method of identifying complex cases based on their individual characteristics.
Clinical records for 1,512 patients accessing low- and high-intensity psychological treatments were partitioned in 2 random subsamples. Prognostic indices predicting post-treatment reliable and clinically significant improvement (RCSI) in depression (Patient Health Questionnaire-9; Kroenke, Spitzer, & Williams, 2001) and anxiety (Generalized Anxiety Disorder-7; Spitzer, Kroenke, Williams, & Löwe, 2006) symptoms were estimated in 1 subsample using penalized (Lasso) regressions with optimal scaling. A PI-based algorithm was used to classify patients as standard (St) or complex (Cx) cases in the second (cross-validation) subsample. RCSI rates were compared between Cx cases that accessed treatments of different intensities using logistic regression.
St cases had significantly higher RCSI rates compared to Cx cases (OR = 1.81 to 2.81). Cx cases tended to attain better depression outcomes if they were initially assigned to high-intensity (vs. low intensity) interventions (OR = 2.23); a similar pattern was observed for anxiety but the odds ratio (1.74) was not statistically significant.
Complex cases could be detected early and matched to high-intensity interventions to improve outcomes. (PsycINFO Database Record
尽管对于如何定义心理护理中的复杂性尚未达成共识,但有些人认为某些情况更为复杂和难以治疗。本研究提出了一种基于个体特征的复杂病例识别的计算、数据驱动方法。
将 1512 名接受低强度和高强度心理治疗的患者的临床记录分为 2 个随机子样本。使用惩罚(lasso)回归进行最优标度估计,在 1 个子样本中估计了预测治疗后抑郁(患者健康问卷-9;Kroenke、Spitzer 和 Williams,2001)和焦虑(广泛性焦虑障碍-7;Spitzer、Kroenke、Williams 和 Löwe,2006)症状后可靠和临床显著改善(RCSI)的预后指标。在第二个(交叉验证)子样本中,使用基于 PI 的算法将患者分类为标准(St)或复杂(Cx)病例。使用逻辑回归比较接受不同强度治疗的 Cx 病例的 RCSI 率。
St 病例的 RCSI 率明显高于 Cx 病例(OR=1.81 至 2.81)。如果 Cx 病例最初被分配到高强度(而非低强度)干预,则更有可能获得更好的抑郁结局(OR=2.23);对于焦虑症,也观察到类似的模式,但优势比(1.74)没有统计学意义。
可以早期发现复杂病例,并将其与高强度干预措施相匹配,以改善治疗效果。