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“对与辩”辩论:医学博士伊桑·鲁索访谈

The Versus Debate: An Interview with Ethan Russo, MD.

作者信息

Piomelli Daniele, Russo Ethan B

机构信息

Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, California.

Department of Drug Discovery and Development, Istituto Italiano di Tecnologia, Genoa, Italy.

出版信息

Cannabis Cannabinoid Res. 2016 Jan 1;1(1):44-46. doi: 10.1089/can.2015.29003.ebr. eCollection 2016.

DOI:10.1089/can.2015.29003.ebr
PMID:28861479
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5576603/
Abstract

Dr. Ethan Russo, MD, is a board-certified neurologist, psychopharmacology researcher, and Medical Director of PHYTECS, a biotechnology company researching and developing innovative approaches targeting the human endocannabinoid system. Previously, from 2003 to 2014, he served as Senior Medical Advisor and study physician to GW Pharmaceuticals for three Phase III clinical trials of Sativex for alleviation of cancer pain unresponsive to optimized opioid treatment and studies of Epidiolex for intractable epilepsy. He has held faculty appointments in Pharmaceutical Sciences at the University of Montana, in Medicine at the University of Washington, and as visiting Professor, Chinese Academy of Sciences. He is a past President of the International Cannabinoid Research Society and former Chairman of the International Association for Cannabinoid Medicines. He serves on the Scientific Advisory Board for the American Botanical Council. He is the author of numerous books, book chapters, and articles on Cannabis, ethnobotany, and herbal medicine. His research interests have included correlations of historical uses of Cannabis with modern pharmacological mechanisms, phytopharmaceutical treatment of migraine and chronic pain, and phytocannabinoid/terpenoid/serotonergic/vanilloid interactions.

摘要

伊桑·鲁索医生,医学博士,是一名获得董事会认证的神经学家、精神药理学研究员,也是PHYTECS公司的医学总监。PHYTECS是一家生物技术公司,致力于研究和开发针对人类内源性大麻素系统的创新方法。此前,在2003年至2014年期间,他担任GW制药公司的高级医学顾问和研究医生,参与了三项关于Sativex缓解对优化阿片类药物治疗无反应的癌症疼痛以及Epidiolex治疗顽固性癫痫的III期临床试验。他曾在蒙大拿大学药学院、华盛顿大学医学院任职,并担任中国科学院客座教授。他曾任国际大麻素研究协会主席和国际大麻素药物协会前主席。他是美国植物委员会科学顾问委员会成员。他撰写了许多关于大麻、民族植物学和草药医学的书籍、章节和文章。他的研究兴趣包括大麻的历史用途与现代药理机制的相关性、偏头痛和慢性疼痛的植物药治疗,以及植物大麻素/萜类/血清素能/香草酸相互作用。

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Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects.驯服四氢大麻酚:潜在的大麻协同作用和植物大麻素-萜烯素增效作用。
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Med Hypotheses. 2006;66(2):234-46. doi: 10.1016/j.mehy.2005.08.026. Epub 2005 Oct 4.
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Nat Prod Rep. 1999 Apr;16(2):131-43. doi: 10.1039/a703973e.
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An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity.一种随从效应:无活性的内源性脂肪酸甘油酯增强2-花生四烯酸甘油酯的大麻素活性。
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Neuroimmunomodulation. 1995 May-Jun;2(3):174-80. doi: 10.1159/000096889.