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革兰氏阴性菌医院分离株对抗菌剂和消毒剂的敏感性比较

Comparative susceptibility of hospital isolates of gram-negative bacteria to antiseptics and disinfectants.

作者信息

Hammond S A, Morgan J R, Russell A D

出版信息

J Hosp Infect. 1987 May;9(3):255-64. doi: 10.1016/0195-6701(87)90122-8.

DOI:10.1016/0195-6701(87)90122-8
PMID:2886530
Abstract

The sensitivity of hospital isolates of Gram-negative bacteria to cationic antiseptics, mercuric chloride and two organomercury compounds has been measured. A comparison was made with laboratory strains of known sensitivity which acted as standards. All strains of Escherichia coli showed a uniformly high sensitivity to chlorhexidine diacetate; other organisms tended to be less sensitive to the biguanide. Quaternary ammonium compounds were less effective than chlorhexidine. Resistance to mercuric chloride was observed frequently, but there was little evidence of organomercurial resistance except in Pseudomonas aeruginosa isolates.

摘要

已对革兰氏阴性菌的医院分离株对阳离子防腐剂、氯化汞和两种有机汞化合物的敏感性进行了测定。与已知敏感性的实验室菌株作为标准进行了比较。所有大肠杆菌菌株对双醋酸氯己定均表现出一致的高敏感性;其他生物体对双胍的敏感性往往较低。季铵化合物的效果不如氯己定。经常观察到对氯化汞的耐药性,但除铜绿假单胞菌分离株外,几乎没有有机汞耐药的证据。

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