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化学消毒剂和防腐剂对耳念珠菌的杀酵母活性。

Yeasticidal activity of chemical disinfectants and antiseptics against Candida auris.

机构信息

Public Health England, National Infection Service, Porton Down, Salisbury, UK.

Department of Microbiology, Royal Brompton Hospital and Harefield NHS Foundation Trust, London, UK.

出版信息

J Hosp Infect. 2017 Dec;97(4):371-375. doi: 10.1016/j.jhin.2017.08.019. Epub 2017 Sep 1.

Abstract

Candida auris appears to be transmitted readily between patients, yet information regarding the efficacy of environmental disinfection and skin decolonization is lacking. A quantitative suspension test (EN 13624:2013) was used to evaluate the yeasticidal activity of different chemical disinfectants and antiseptics against C. auris and Candida albicans. When tested in suspension, both a chlorine-based disinfectant and iodine-based skin antiseptic were effective against C. auris, suggesting that their use could reduce environmental contamination and skin colonization, respectively, if applied appropriately. Chlorhexidine-based products may also be effective. However, in this study, activity depended on formulation, specifically the presence of isopropyl alcohol.

摘要

耳念珠菌似乎很容易在患者之间传播,但缺乏有关环境消毒和皮肤去定植效果的信息。采用定量悬浮试验(EN 13624:2013)评估了不同化学消毒剂和防腐剂对耳念珠菌和白色念珠菌的杀菌活性。在悬浮液中测试时,含氯消毒剂和含碘皮肤消毒剂均对耳念珠菌有效,这表明如果使用得当,它们的使用可以分别减少环境污染和皮肤定植。基于洗必泰的产品也可能有效。然而,在这项研究中,其活性取决于配方,特别是异丙醇的存在。

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