Parisi Pasquale, Paolino Maria Chiara, Raucci Umberto, Ferretti Alessandro, Villa Maria Pia, Trenite Dorothee Kasteleijn-Nolst
Child Neurology, Headache Paediatric Center, Paediatric Sleep Disorders, NESMOS Department, Chair of Pediatrics, Faculty of Medicine and Psychology, Sapienza University, c/o Sant'Andrea Hospital, Rome, Italy.
Child Neurology, Headache Paediatric Center, Paediatric Sleep Disorders, NESMOS Department, Chair of Pediatrics, Faculty of Medicine and Psychology, Sapienza University, c/o Sant'Andrea Hospital, Rome, Italy.
Epilepsy Behav. 2017 Oct;75:165-169. doi: 10.1016/j.yebeh.2017.08.001. Epub 2017 Sep 1.
Benign epilepsy with centrotemporal spikes (BECTS) epilepsy, also known as rolandic epilepsy, is the most common childhood type of epilepsy. There is debate on its "benign" definition given the numerous literature data on its correlation to cognitive morbidity. Although its prognosis is often favorable, BECTS can present or evolve however to an atypical form, characterized by a worse prognosis and negative impact on cognitive development. It is possible that abnormal electrical activity, marker of neurological dysfunction, has the potential to disrupt neural network function and development. Numerous studies tried to identify clinical or electroencephalographic criteria for atypical forms and atypical evolution of BECTS in order to guide follow-up and treatment of patients and to predict their outcome. This review provides a compact summery of literature data with a focus on predictive features of future cognitive decline.
伴有中央颞区棘波的良性癫痫（BECTS），也称为罗兰多癫痫，是儿童期最常见的癫痫类型。鉴于大量关于其与认知发病率相关性的文献数据，对于其“良性”定义存在争议。尽管其预后通常良好，但BECTS可能会呈现或演变为非典型形式，其特征是预后较差且对认知发育有负面影响。神经功能障碍的标志物——异常电活动有可能破坏神经网络功能和发育。许多研究试图确定BECTS非典型形式和非典型演变的临床或脑电图标准，以指导患者的随访和治疗，并预测其预后。本综述对文献数据进行了简要总结，重点关注未来认知衰退的预测特征。
