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儿童原发性骨质疏松症。

Primary osteoporosis in children.

作者信息

Tan Lay Ong, Lim Soo Yen, Vasanwala Rashida Farhad

机构信息

Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore.

Department of Family Medicine, SingHealth Polyclinics, Singapore, Singapore.

出版信息

BMJ Case Rep. 2017 Sep 1;2017:bcr-2017-220700. doi: 10.1136/bcr-2017-220700.

Abstract

Osteoporosis in childhood is uncommon, and it may be secondary to a spectrum of diverse conditions. Idiopathic juvenile osteoporosis is a primary osteoporosis of unknown aetiology present in previously well children and is a diagnosis of exclusion. We describe a 10-year-old prepubertal boy who presented with back pain of 1-week duration. His spinal X-ray showed generalised loss of vertebral body heights in keeping with osteoporosis. Endocrine and haematological work-up were normal. He was treated with vitamin D supplement and intravenous pamidronate. This case illustrates the general work-up and causes for paediatric osteoporosis, and the management for idiopathic juvenile osteoporosis.

摘要

儿童骨质疏松症并不常见,它可能继发于一系列不同的病症。特发性青少年骨质疏松症是一种病因不明的原发性骨质疏松症,见于此前健康的儿童,是一种排除性诊断。我们描述了一名10岁青春期前男孩,他出现了持续1周的背痛。他的脊柱X线显示椎体高度普遍降低,符合骨质疏松症表现。内分泌和血液学检查均正常。他接受了维生素D补充剂和静脉注射帕米膦酸盐治疗。该病例说明了儿童骨质疏松症的一般检查、病因以及特发性青少年骨质疏松症的治疗方法。

相似文献

1
Primary osteoporosis in children.儿童原发性骨质疏松症。
BMJ Case Rep. 2017 Sep 1;2017:bcr-2017-220700. doi: 10.1136/bcr-2017-220700.
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Pamidronate treatment of hypercalcemia caused by vitamin D toxicity.帕米膦酸盐治疗维生素D中毒引起的高钙血症。
J Pediatr Endocrinol Metab. 2007 Nov;20(11):1241-8. doi: 10.1515/jpem.2007.20.11.1241.

本文引用的文献

2
Idiopathic Juvenile Osteoporosis: A Case Report.特发性青少年骨质疏松症:一例报告
J Clin Diagn Res. 2015 Aug;9(8):ZD10-2. doi: 10.7860/JCDR/2015/12928.6358. Epub 2015 Aug 1.
6
Bisphosphonates use in children.双膦酸盐类药物在儿童中的应用。
Clin Pediatr (Phila). 2012 Nov;51(11):1011-24. doi: 10.1177/0009922812452118. Epub 2012 Aug 30.
8
Osteoporosis in pediatrics.小儿骨质疏松症
Pediatr Rev. 2001 Feb;22(2):56-65. doi: 10.1542/pir.22-2-56.
10
Idiopathic juvenile osteoporosis.特发性青少年骨质疏松症
Ann N Y Acad Sci. 2000;900:409-12. doi: 10.1111/j.1749-6632.2000.tb06253.x.

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