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需要麻醉支持的妊娠期罕见肝病:一例重度妊娠剧吐病例

Unique Liver Disease of Pregnancy Requiring Anaesthesia Support: A Case with Severe Hyperemesis Gravidarum.

作者信息

Günaydın Berrin, Özek Aykut, Özterlemez Naciye Türk, Tuna Ayca Taş

机构信息

Department of Anaesthesiology, Gazi University School of Medicine, Ankara, Turkey.

Department of Obstetrics and Gynecology, Gazi University School of Medicine, Ankara, Turkey.

出版信息

Turk J Anaesthesiol Reanim. 2017 Aug;45(4):234-236. doi: 10.5152/TJAR.2017.65768. Epub 2017 Aug 1.

DOI:10.5152/TJAR.2017.65768
PMID:28868172
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5579218/
Abstract

Hyperemesis gravidarum (HG) is one of the common unique liver diseases that occurs during pregnancy. Mild cases can be spontaneously resolved in time but severe cases usually require supportive medical treatment to relieve symptoms. Moreover, differential diagnosis may be required in severe cases that manifest with persistent nausea-vomiting, dehydration and weight loss refractory to treatment. Thus, to rule out any gastrointestinal pathology, this case was referred to the outpatient anaesthesia clinic after the first unsuccessful awake endoscopy attempt without sedation. Therefore, anaesthetic support for endoscopy of a pregnant woman with severe HG was presented in this case report.

摘要

妊娠剧吐(HG)是孕期常见的独特肝脏疾病之一。轻症病例可及时自行缓解,但重症病例通常需要支持性药物治疗以缓解症状。此外,对于表现为持续性恶心呕吐、脱水及治疗难以控制的体重减轻的重症病例,可能需要进行鉴别诊断。因此,为排除任何胃肠道病变,在首次未使用镇静剂的清醒内镜检查尝试失败后,该病例被转诊至门诊麻醉科。因此,本病例报告介绍了对一名患有重症HG的孕妇进行内镜检查的麻醉支持情况。

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本文引用的文献

1
Sedation and anaesthesia for non-obstetric surgery.非产科手术的镇静与麻醉
Anaesth Crit Care Pain Med. 2016 Oct;35 Suppl 1:S35-S41. doi: 10.1016/j.accpm.2016.06.009. Epub 2016 Jul 2.
2
Anesthesia for patients with liver disease.肝病患者的麻醉
Hepat Mon. 2014 Jul 1;14(7):e19881. doi: 10.5812/hepatmon.19881. eCollection 2014 Jul.
3
Interventions for nausea and vomiting in early pregnancy.孕早期恶心和呕吐的干预措施。
Cochrane Database Syst Rev. 2014 Mar 21(3):CD007575. doi: 10.1002/14651858.CD007575.pub3.
4
Safety of procedural sedation in pregnancy.孕期程序性镇静的安全性。
J Obstet Gynaecol Can. 2013 Feb;35(2):168-173. doi: 10.1016/S1701-2163(15)31023-9.
5
Guidelines for endoscopy in pregnant and lactating women.孕妇和哺乳期妇女内镜检查指南。
Gastrointest Endosc. 2012 Jul;76(1):18-24. doi: 10.1016/j.gie.2012.02.029. Epub 2012 May 12.
6
Consequences of hyperemesis gravidarum for offspring: a systematic review and meta-analysis.妊娠剧吐对后代的影响:系统评价和荟萃分析。
BJOG. 2011 Oct;118(11):1302-13. doi: 10.1111/j.1471-0528.2011.03023.x. Epub 2011 Jul 12.
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Pregnancy-associated liver disorders.妊娠相关肝脏疾病
Dig Dis Sci. 2008 Sep;53(9):2334-58. doi: 10.1007/s10620-007-0167-9. Epub 2008 Feb 7.
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Liver diseases unique to pregnancy.妊娠期特有的肝脏疾病。
Best Pract Res Clin Gastroenterol. 2007;21(5):771-92. doi: 10.1016/j.bpg.2007.05.004.
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ACOG (American College of Obstetrics and Gynecology) Practice Bulletin: nausea and vomiting of pregnancy.美国妇产科医师学会(ACOG)实践公告:妊娠恶心和呕吐
Obstet Gynecol. 2004 Apr;103(4):803-14.