妊娠期特有的肝脏疾病。

Liver diseases unique to pregnancy.

作者信息

Schutt Vivian A, Minuk Gerald Y

机构信息

Department of Obstetrics and Gynecology, University of Buenos Aires, Buenos Aires, Argentina.

出版信息

Best Pract Res Clin Gastroenterol. 2007;21(5):771-92. doi: 10.1016/j.bpg.2007.05.004.

DOI:10.1016/j.bpg.2007.05.004

PMID:17889807

Abstract

Liver injury and dysfunction in a pregnant woman may be caused by intrinsic features of the pregnancy itself, disorders that are coincidental with pregnancy or pre-existing liver disease that is exacerbated by pregnancy. The clinical setting, gestational age and standard liver biochemistry testing are useful tools in helping to establish a diagnosis. Prompt recognition of the signs of liver disease in pregnant patients leads to timely management and may save the life of both mother and baby. This review summarises the incidence, risk factors, pathogenesis, clinical presentation, diagnosis, treatment and outcome of those liver diseases unique to pregnancy.

摘要

孕妇的肝损伤和功能障碍可能由妊娠本身的内在特征、与妊娠同时发生的疾病或因妊娠而加重的原有肝病引起。临床情况、孕周和标准肝脏生化检查是有助于确立诊断的有用工具。及时识别孕妇肝病的体征可实现及时管理，并可能挽救母婴生命。本综述总结了妊娠特有的肝病的发病率、危险因素、发病机制、临床表现、诊断、治疗及转归。