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自我报告出生体重的有效性:来自挪威双胞胎样本的结果。

Validity of Self-Reported Birth Weight: Results from a Norwegian Twin Sample.

作者信息

Nilsen Thomas S, Kutschke Julia, Brandt Ingunn, Harris Jennifer R

机构信息

Department for Cohort Studies,Norwegian Institute of Public Health,Oslo,Norway.

Medical Department,Vestfold Hospital Trust,Tønsberg,Norway.

出版信息

Twin Res Hum Genet. 2017 Oct;20(5):406-413. doi: 10.1017/thg.2017.44. Epub 2017 Sep 4.

DOI:10.1017/thg.2017.44
PMID:28868992
Abstract

The association between birth weight and later life outcomes is of considerable interest in life-course epidemiology. Research often relies on self-reported measures of birth weight, and its validity is consequently of importance. We assessed agreement between self-reported birth weight and official birth records for Norwegian twins born 1967-1974. The intraclass correlation between self-reported birth weight and register-based birth weight was 0.91 in our final sample of 363 twins. It could be expected that 95% of self-reported birth-weight values will deviate from official records within a maximum of +446 grams and a minimum of -478 grams - around a mean deviation of 16 grams. Self-reported birth weight had a sensitivity of 0.78-0.89 and a positive predictive value of 0.59-0.85, and an overall weighted kappa of 0.71. We further assessed agreement by conducting two linear regression models where we respectively regressed self-reported birth weight and register-based birth weight on adult body mass index, a known association. The two models were not significantly different; however, there were different levels of significance in parameter estimates that warrant some caution in using self-reported birth weight. Reliability of self-reported birth weight was also assessed, based on self-reports in another sample of twins born 1935-1960 who had reported their birth weight in two questionnaires 34 years apart. The intraclass correlation was 0.86, which indicates a high degree of reliability. In conclusion, self-reported birth weight, depending on context and age when birth weight was reported, can be cautiously used.

摘要

出生体重与晚年生活结局之间的关联在生命历程流行病学中备受关注。研究通常依赖于自我报告的出生体重测量值,因此其有效性至关重要。我们评估了1967年至1974年出生的挪威双胞胎自我报告的出生体重与官方出生记录之间的一致性。在我们最终的363对双胞胎样本中,自我报告的出生体重与基于登记处的出生体重之间的组内相关性为0.91。可以预期,95%的自我报告出生体重值与官方记录的偏差最大为+446克,最小为-478克,平均偏差约为16克。自我报告的出生体重敏感性为0.78 - 0.89,阳性预测值为0.59 - 0.85,总体加权kappa值为0.71。我们通过进行两个线性回归模型进一步评估了一致性,在这两个模型中,我们分别将自我报告的出生体重和基于登记处的出生体重对成人身体质量指数进行回归,成人身体质量指数是一个已知的关联因素。这两个模型没有显著差异;然而,参数估计的显著性水平不同,这使得在使用自我报告的出生体重时需要谨慎。我们还基于1935年至1960年出生的另一组双胞胎样本中的自我报告评估了自我报告出生体重的可靠性,这些双胞胎在相隔34年的两份问卷中报告了他们的出生体重。组内相关性为0.86,这表明可靠性程度较高。总之,根据报告出生体重时的背景和年龄,自我报告的出生体重可以谨慎使用。

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