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[粪便微生物群移植治疗肠道疾病]

[Faecal microbiota transplantation for the treatment of bowel disease].

作者信息

Rode Anne A, Chehri Mahtab, Petersen Andreas Munk, Bytzer Peter

出版信息

Ugeskr Laeger. 2017 Jul 31;179(31).

Abstract

Faecal microbiota transplantation (FMT) is the transferral of faeces from a healthy donor to a patient with a disease linked to disturbances in the gut microbiota. The treatment has been implemented at several hospitals in Denmark, and banks with frozen donor stool material have been established. The effect of FMT for recurrent Clostridium difficile infection is well-documented. FMT cannot be recommended for routine clinical use for inflammatory bowel disease and irritable bowel syndrome because of lack of data from clinical trials.

摘要

粪便微生物群移植(FMT)是将健康供体的粪便转移到患有与肠道微生物群紊乱相关疾病的患者体内。丹麦的几家医院已经实施了这种治疗方法,并且建立了储存冷冻供体粪便样本的库。FMT对复发性艰难梭菌感染的疗效已有充分记录。由于缺乏临床试验数据,不建议将FMT用于炎症性肠病和肠易激综合征的常规临床治疗。

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