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基于石墨烯的纳米材料在药物和/或基因传递、生物成像和组织工程中的应用。

Graphene-based nanomaterials for drug and/or gene delivery, bioimaging, and tissue engineering.

机构信息

John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA; Research Institute of Petroleum Processing, SINOPEC, Beijing 100083, China.

John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.

出版信息

Drug Discov Today. 2017 Sep;22(9):1302-1317. doi: 10.1016/j.drudis.2017.04.002. Epub 2017 Sep 1.

Abstract

Here, we discuss the biomedical applications of graphene-based nanomaterials (GBNs). We examine graphene and its various derivatives, including graphene, graphene oxides (GOs), reduced graphene oxides (rGOs), graphene quantum dots (GQDs), and graphene composites, and discuss their unique properties related to their biomedical applications. We also summarize the detailed biomedical applications of GBNs, including drug and/or gene delivery, bioimaging, and tissue engineering. We also highlight the toxicity of these nanomaterials.

摘要

在这里,我们讨论了基于石墨烯的纳米材料(GBNs)在生物医学中的应用。我们研究了石墨烯及其各种衍生物,包括石墨烯、氧化石墨烯(GOs)、还原氧化石墨烯(rGOs)、石墨烯量子点(GQDs)和石墨烯复合材料,并讨论了它们与生物医学应用相关的独特性质。我们还总结了 GBNs 的详细生物医学应用,包括药物和/或基因递送、生物成像和组织工程。我们还强调了这些纳米材料的毒性。

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