Aoe Seiichiro, Ichinose Yasunori, Kohyama Noriko, Komae Kozo, Takahashi Asuka, Abe Daigo, Yoshioka Toji, Yanagisawa Takashi
Department of Food Science, Otsuma Women's University, Tokyo, Japan.
Institute of Crop Science, National Agriculture and Food Research Organization, Tsukuba, Japan.
Nutrition. 2017 Oct;42:1-6. doi: 10.1016/j.nut.2017.05.002. Epub 2017 May 15.
The aim of this study was to investigate whether a diet in which high β-glucan barley was substituted for rice would reduce visceral fat obesity in Japanese individuals.
A randomized, double-blind, placebo-controlled intervention study was conducted with 100 Japanese individuals with waist circumference (WC) ≥85 cm for men or ≥90 cm for women and body mass index (BMI) ≥24 kg/m. Participants were randomly assigned to consume a mixture of rice and either high β-glucan barley (test group, 4.4 g/d) or β-glucan-free barley (placebo group) for 12 wk. Blood samples and computed tomography scans were obtained before and after the trial.
Both groups showed decreases in body weight and BMI, and these changes were significantly greater in the test group. WC and visceral fat area (VFA) significantly decreased in both groups (VFA: -10.7 cm in the test group; -6.8 cm in the placebo group). These changes did not differ significantly between the groups. However, a subgroup analysis of participants with VFA ≥100 cm showed a significant decrease in the test group, and this decrease was significantly greater than in the placebo group.
The intake of high β-glucan barley led to significant and safe reductions in VFA, body weight, BMI, and WC in individuals with visceral fat obesity with VFA ≥100 cm. Barley high in β-glucan may contribute to preventing visceral fat obesity.
本研究旨在调查用高β-葡聚糖大麦替代大米的饮食是否会减少日本人群的内脏脂肪型肥胖。
对100名腰围（WC）男性≥85厘米或女性≥90厘米且体重指数（BMI）≥24千克/平方米的日本个体进行了一项随机、双盲、安慰剂对照干预研究。参与者被随机分配食用大米与高β-葡聚糖大麦（试验组，4.4克/天）或无β-葡聚糖大麦（安慰剂组）的混合物，为期12周。在试验前后采集血样并进行计算机断层扫描。
两组体重和BMI均下降，试验组的这些变化显著更大。两组的WC和内脏脂肪面积（VFA）均显著下降（试验组VFA：-10.7平方厘米；安慰剂组-6.8平方厘米）。两组之间的这些变化无显著差异。然而，对VFA≥100平方厘米的参与者进行的亚组分析显示，试验组有显著下降，且该下降显著大于安慰剂组。
摄入高β-葡聚糖大麦可使VFA≥100平方厘米的内脏脂肪型肥胖个体的VFA、体重、BMI和WC显著且安全地降低。高β-葡聚糖大麦可能有助于预防内脏脂肪型肥胖。
