Shimizu Chikako, Kihara Makoto, Aoe Seiichiro, Araki Shigeki, Ito Kazutoshi, Hayashi Katsuhiro, Watari Junji, Sakata Yukikuni, Ikegami Sachie
Frontier Laboratories of Value Creation, Sapporo Breweries Ltd., 10 Okatohme, Yaizu, Shizuoka, 425-0013, Japan.
Plant Foods Hum Nutr. 2008 Mar;63(1):21-5. doi: 10.1007/s11130-007-0064-6. Epub 2007 Dec 12.
This study investigated whether the consumption of a diet in which high-beta-glucan barley replaced rice would reduce the visceral fat area as well as the serum low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) in hypercholesterolemic Japanese men. A randomized, double-blinded, placebo-controlled intervention study was conducted in 44 hypercholesterolemic Japanese men with a body mass index (BMI) >22 kg/m2. The subjects were randomly assigned to groups consuming either rice (placebo group) or a mixture of rice and pearl barley with a high beta-glucan content (test group, 7.0 g beta-glucan per day) for 12 weeks. Blood samples were taken, and CT scan obtained before the trial and every four weeks during the trial. The pearl barley intake significantly reduced serum concentrations of LDL-C (P = 0.041) and TC (P = 0.037) during the trial. Significant differences between the test and placebo groups were found for the visceral fat (P = 0.039), BMI (P = 0.015), and waist circumference (P = 0.011) at the end point. The consumption of pearl barley with a high beta-glucan content reduces not only LDL-C but also visceral fat area.
本研究调查了用高β-葡聚糖大麦替代大米的饮食是否会减少高胆固醇血症日本男性的内脏脂肪面积以及血清低密度脂蛋白胆固醇（LDL-C）和总胆固醇（TC）。对44名体重指数（BMI）>22kg/m²的高胆固醇血症日本男性进行了一项随机、双盲、安慰剂对照干预研究。受试者被随机分为两组，一组食用大米（安慰剂组），另一组食用大米和高β-葡聚糖含量的珍珠大麦混合物（试验组，每天7.0gβ-葡聚糖），为期12周。在试验前以及试验期间每四周采集血样并进行CT扫描。在试验期间，珍珠大麦的摄入显著降低了血清LDL-C（P = 0.041）和TC（P = 0.037）的浓度。在终点时，试验组和安慰剂组在内脏脂肪（P = 0.039）、BMI（P = 0.015）和腰围（P = 0.011）方面存在显著差异。食用高β-葡聚糖含量的珍珠大麦不仅能降低LDL-C，还能减少内脏脂肪面积。
