Suppr超能文献

腔静脉滤器取出率及与在美国大样本中取出相关的因素。

Vena Cava Filter Retrieval Rates and Factors Associated With Retrieval in a Large US Cohort.

机构信息

Department of Pharmacy Practice and Science, University of Kentucky College of Pharmacy, Lexington, KY

Department of Pharmaceutical Outcomes and Policy, University of Florida College of Pharmacy, Gainesville, FL.

出版信息

J Am Heart Assoc. 2017 Sep 4;6(9):e006708. doi: 10.1161/JAHA.117.006708.

Abstract

BACKGROUND

Retrieval of vena cava filters (VCFs) is important for safety as complications increase with longer dwell times. This study assessed VCF retrieval rates and factors associated with retrieval in a national cohort.

METHODS AND RESULTS

VCFs were identified by procedural codes from an administrative claims database. Patients were identified who had a VCF placement during a hospitalization from a national commercial administrative claims database. Indications for VCF placement were identified as pulmonary embolism with or without deep vein thrombosis, deep vein thrombosis only, or prophylactic. Patient demographic and clinical characteristics were included in proportional hazard regression models to find associations with early (90-day) and 1-year VCF retrieval. Initiation of anticoagulation and the correlation between time-to-retrieval and time-to-initiation of anticoagulation were observed. Of 54 766 patients receiving a VCF, 36.9% had pulmonary embolism, 43.9% had deep vein thrombosis only, and 19.2% had no apparent venous thromboembolism present. Over the 1 year of follow-up, the cumulative incidence of VCF retrieval was 18.4%. Retrieval increased over time from a low of 14.0% in 2010 up to ≈24% in 2014. In adjusted time-to-event models, increasing age, differing regions, and some comorbidities were associated with poorer retrieval rates. Initiation of anticoagulation was poorly correlated with retrieval, with anticoagulation preceding retrieval by a median of 51 days while those without retrieval had a median of 278 days of exposure to anticoagulation.

CONCLUSIONS

VCF retrieval increased over the study period but remained suboptimal and was weakly correlated with anticoagulation initiation.

摘要

背景

由于留置时间越长并发症增加,因此回收腔静脉滤器(VCF)对于安全性很重要。本研究评估了全国队列中 VCF 回收率和与回收相关的因素。

方法和结果

通过行政索赔数据库中的程序代码确定 VCF。从全国商业行政索赔数据库中确定了在住院期间放置 VCF 的患者。VCF 放置的适应证为肺栓塞伴或不伴深静脉血栓形成、单纯深静脉血栓形成或预防性。将患者的人口统计学和临床特征纳入比例风险回归模型,以发现与早期(90 天)和 1 年 VCF 回收相关的因素。观察了抗凝的开始以及与回收时间和抗凝开始时间之间的相关性。在接受 VCF 的 54766 例患者中,36.9%有肺栓塞,43.9%仅有深静脉血栓形成,19.2%没有明显的静脉血栓栓塞症。在 1 年的随访中,VCF 回收的累积发生率为 18.4%。从 2010 年的低值 14.0%到 2014 年的约 24%,回收随时间增加。在调整后的时间事件模型中,年龄增长、不同地区和一些合并症与较低的回收率相关。抗凝的开始与回收相关性较差,抗凝的中位数时间比回收早 51 天,而未进行回收的患者的抗凝中位数时间为 278 天。

结论

在研究期间,VCF 回收有所增加,但仍不理想,且与抗凝开始的相关性较弱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ba3/5634307/fead92418aef/JAH3-6-e006708-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验