Maskey-Warzęchowska Marta, Chojnowska Magdalena, Ptaszyński Konrad, Rubinsztajn Renata, Padzik-Moczydłowska Marzena, Krenke Rafał
Department of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw.
Adv Respir Med. 2017;85(4):211-215. doi: 10.5603/ARM.2017.0035.
Benign metastasising leiomyoma (BML) is characterised by extrauterine smooth muscle tumours in women after surgical treatment for uterine leiomyoma. Usually manifested as solitary or multiple focal lesions in various organs, it imposes a scrutinous diagnostic work-up to exclude a malignant disease and requires confirmation in microscopic examination of the extrauterine focus. The authors present a case of a 56-year-old woman with BML manifesting as bilateral multiple pulmonary nodules, with a tentative diagnosis of a disseminated malignant disease of mesenchymal origin. The patient underwent multiple diagnostic tests, which excluded malignancy. The definite diagnosis was established after the microscopic reevaluation of an excised pulmonary nodule. The patient is monitored with chest magnetic resonance. BML should be considered in the differential diagnosis of multiple pulmonary nodules in asymptomatic women. Patients with BML require long-term monitoring, therefore the selected imaging method should not carry the risk of cumulative side effects.
良性转移性平滑肌瘤(BML)的特征是子宫平滑肌瘤手术治疗后的女性出现子宫外平滑肌肿瘤。通常表现为各个器官中的单个或多个局灶性病变,需要进行仔细的诊断检查以排除恶性疾病,并且需要在子宫外病灶的显微镜检查中得到证实。作者报告了一例56岁患有BML的女性,表现为双侧多发性肺结节,初步诊断为间叶源性播散性恶性疾病。该患者接受了多项诊断检查,排除了恶性肿瘤。在对切除的肺结节进行显微镜重新评估后确定了明确诊断。该患者接受胸部磁共振成像监测。在无症状女性多发性肺结节的鉴别诊断中应考虑BML。BML患者需要长期监测,因此所选的成像方法不应有累积副作用的风险。