Suppr超能文献

择期腹主动脉瘤手术拒诊后的结局。

Outcome after Turndown for Elective Abdominal Aortic Aneurysm Surgery.

机构信息

Department of Vascular Surgery, Black Country Vascular Network, Russell's Hall Hospital, Dudley, UK.

Department of Vascular Surgery, Black Country Vascular Network, Russell's Hall Hospital, Dudley, UK.

出版信息

Eur J Vasc Endovasc Surg. 2017 Nov;54(5):579-586. doi: 10.1016/j.ejvs.2017.07.023. Epub 2017 Sep 2.

Abstract

OBJECTIVES

The aim was to assess the survival of patients who had been turned down for repair of an abdominal aortic aneurysm (AAA) and to examine the factors influencing this.

METHODS

This was a retrospective observational study of a prospectively maintained database of all patients turned down for AAA intervention by the Black Country Vascular Network multidisciplinary team (MDT) from January 2013 to December 2015. Data on AAA size, cardiopulmonary exercise testing (CPET) and cause of death were recorded.

RESULTS

There were 112 patients. The median age at turndown was 83.9 years (IQR 10.2 years). The median AAA size at turndown was 63 mm (IQR 16.7 mm). The median follow-up time after turndown was 324 days (IQR 537.5 days). Sixty-four patients (57.1%) were deceased after 2 years, with a median survival time of 462 days (IQR 579 days). Patients who died had a significantly larger AAA dimension (median 65 mm, IQR 18.5 mm) than those surviving to date (median 59 mm, IQR 10 mm, p = .004). Using Cox regression analysis, the probability of 1 year survival in the whole population was 0.614. The probability of 2 year survival was 0.388. When accounting for age, gender, AAA dimension, and British Aneurysm Repair risk score, no factors had significant influence over survival. Of the 64 deceased patients, 30 had an accessible cause of death: 36.7% of these were due to ruptured AAAs. There was no significant difference in AAA size between those dying of ruptures and those dying of other causes (p = .225, mean 74 mm and 67 mm respectively).

CONCLUSIONS

Being turned down for AAA repair carries a significant short-term risk of mortality. Those turned down for repair carried significant levels of comorbid disease but no factors considered were found to be independently predictive of the length of survival.

摘要

目的

评估因腹主动脉瘤(AAA)修复而被拒绝的患者的生存率,并探讨影响生存率的因素。

方法

这是一项回顾性观察性研究,纳入了 2013 年 1 月至 2015 年 12 月期间被黑乡血管网络多学科团队(MDT)拒绝 AAA 干预的所有患者的前瞻性维护数据库中的数据。记录 AAA 大小、心肺运动测试(CPET)和死因数据。

结果

共有 112 名患者。拒绝时的中位年龄为 83.9 岁(IQR 10.2 岁)。拒绝时的 AAA 大小中位数为 63mm(IQR 16.7mm)。拒绝后的中位随访时间为 324 天(IQR 537.5 天)。2 年后有 64 名患者(57.1%)死亡,中位生存时间为 462 天(IQR 579 天)。死亡患者的 AAA 尺寸明显大于存活至今的患者(中位数 65mm,IQR 18.5mm 与中位数 59mm,IQR 10mm,p=0.004)。使用 Cox 回归分析,全人群 1 年生存率为 0.614。2 年生存率为 0.388。当考虑年龄、性别、AAA 尺寸和英国动脉瘤修复风险评分时,没有因素对生存率有显著影响。在 64 名死亡患者中,有 30 名患者死因可查:36.7%死于破裂的 AAA。破裂组和其他原因死亡组的 AAA 大小无显著差异(p=0.225,分别为 74mm 和 67mm)。

结论

因 AAA 修复而被拒绝带来显著的短期死亡风险。被拒绝进行修复的患者存在严重的合并症,但没有发现任何因素可独立预测生存时间。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验