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用于双光子激发下线粒体多模态磷光成像的近红外发光铱(III)配合物的合理设计

Rational design of NIR-emitting iridium(iii) complexes for multimodal phosphorescence imaging of mitochondria under two-photon excitation.

作者信息

Jin Chengzhi, Guan Ruilin, Wu Jingheng, Yuan Bo, Wang Lili, Huang Juanjuan, Wang Hui, Ji Liangnian, Chao Hui

机构信息

MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.

School of Physics, Sun Yat-Sen University, Guangzhou 510275, P. R. China.

出版信息

Chem Commun (Camb). 2017 Sep 25;53(75):10374-10377. doi: 10.1039/c7cc05193j. Epub 2017 Sep 6.

Abstract

A series of NIR-emitting iridium(iii) complexes were developed for multimodal phosphorescence imaging (NIR imaging, phosphorescence lifetime imaging and time-gated imaging) of mitochondria in living cells, 3D multicellular spheroids (MTCCs) and hippocampus slice under two-photon excitation.

摘要

开发了一系列近红外发射铱(III)配合物,用于在双光子激发下对活细胞、3D多细胞球体(MTCCs)和海马体切片中的线粒体进行多模态磷光成像(近红外成像、磷光寿命成像和时间门控成像)。

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