Sohaili Aarman, Morre Servaas A, Thomas Pierre P M
Institute of Public Health Genomics, Genetics and Cell Biology Cluster, GROW Research School for Oncology and Development Biology, Maastricht University, Maastricht, Limburg, The Netherlands.
Institute of Public Health Genomics, Genetics and Cell Biology Cluster, GROW Research School for Oncology and Development Biology, Maastricht University, Universiteitssingel 50, Maastricht, Limburg 6229 ER, The Netherlands.
Ther Adv Reprod Health. 2024 Dec 19;18:26334941241305825. doi: 10.1177/26334941241305825. eCollection 2024 Jan-Dec.
(CT), a Gram-negative intracellular bacterium, is differentiated into three biovars associated with distinct clinical syndromes, ranging from trachoma, the world's cause of preventable blindness, to the most common sexually transmitted infection. This variability underscores CT's significant impact on public health, particularly in low-resource settings. In Kenya, where the demographic is predominantly younger, the burden of CT remains poorly understood and potentially underestimated.
This study aimed to assess the prevalence of both sexually transmitted and ocular CT across various regions and populations within Kenya.
Articles on CT population testing and laboratory detection, from 2014 to date, in English or Swahili only.
Electronic databases of PubMed and Google Scholar were used.
A scoping review.
This study conducted a systematic scoping review, following Arksey and O'Malley's framework and adhering to PRISMA guidelines for scoping reviews (PRISMA-ScR).
This study incorporates findings from 19 original studies on sexually transmitted CT and seven on ocular CT. CT prevalence for four identified populations: sexually active females 2%-13%, men who have sex with men 1.3%-51%, pregnant women 2.5%-14.9% and other population groups 2.8%-16.4%. By contrast, studies on ocular CT, all performed in rural settings, found prevalence surpassing the WHO's 10% threshold primarily amongst children and mothers.
The variability in CT prevalence across different demographics and geographical regions emphasizes the impact of socio-economic, environmental and diagnostic factors on disease transmission and detection. The insights gained here can serve as a foundation for evidence-based health policies and interventions aimed at mitigating the burden of CT in Kenya.
沙眼衣原体（CT）是一种革兰氏阴性胞内细菌，可分为三种生物变种，与不同的临床综合征相关，从导致全球可预防失明的沙眼到最常见的性传播感染。这种变异性凸显了CT对公共卫生的重大影响，尤其是在资源匮乏的地区。在肯尼亚，人口结构以年轻人为主，CT的负担仍知之甚少且可能被低估。
本研究旨在评估肯尼亚不同地区和人群中性传播和眼部CT的流行情况。
2014年至今仅用英文或斯瓦希里语撰写的关于CT人群检测和实验室检测的文章。
使用了PubMed和谷歌学术的电子数据库。
一项范围综述。
本研究按照Arksey和O'Malley的框架并遵循范围综述的PRISMA指南（PRISMA-ScR）进行了系统的范围综述。
本研究纳入了19项关于性传播CT的原始研究和7项关于眼部CT的原始研究的结果。四个已确定人群的CT流行率：性活跃女性为2%-13%，男男性行为者为1.3%-51%，孕妇为2.5%-14.9%，其他人群为2.8%-16.4%。相比之下，所有在农村地区进行的眼部CT研究发现，患病率主要在儿童和母亲中超过了世界卫生组织设定的10%的阈值。
CT在不同人口统计学和地理区域的流行率差异强调了社会经济、环境和诊断因素对疾病传播和检测的影响。此处获得的见解可为旨在减轻肯尼亚CT负担的循证卫生政策和干预措施奠定基础。
