From the *Melbourne Sexual Health Centre, Alfred Health; and †Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Sex Transm Dis. 2017 Oct;44(10):593-595. doi: 10.1097/OLQ.0000000000000654.
Use of alcohol-containing mouthwash has been found to have an inhibitory effect against pharyngeal gonorrhoea. The aim of this study was to investigate the association between self-reported mouthwash use and pharyngeal gonorrhoea detection among men who have sex with men (MSM).
A cross-sectional survey was conducted between March 23, 2015, and June 30, 2015 among MSM attending the Melbourne Sexual Health Centre in Australia. Men who have sex with men were invited to complete a short questionnaire on mouthwash use and they were also tested for pharyngeal gonorrhoea by nucleic acid amplification test. Multivariate logistic regression was performed to examine the association between mouthwash use and pharyngeal gonorrhoea detection.
Of the 823 MSM, pharyngeal gonorrhoea detection decreased significantly with increasing age group (≤24 years, 14.5%; 25-34 years, 10.7%; ≥35 years, 6.0%; ptrend = 0.003). The proportion reporting daily use of mouthwash increased significantly with increasing age group (from 10.1% to 14.5% to 19.8%; ptrend = 0.005). However, there was no significant association between pharyngeal gonorrhoea detection and daily use of mouthwash after adjusting for age, number of male sexual partners, human immunodeficiency virus status, and type of mouthwash use.
Although the proportion of daily use of mouthwash increased with age, and pharyngeal gonorrhoea detection decreased with age, the association between self-reported mouthwash use and pharyngeal gonorrhoea detection by nucleic acid amplification test was not statistically significant.
含酒精漱口水的使用已被发现对咽部淋病具有抑制作用。本研究旨在调查男男性行为者（MSM）自我报告的漱口水使用与咽淋病检测之间的关联。
2015 年 3 月 23 日至 2015 年 6 月 30 日，在澳大利亚墨尔本性健康中心对 MSM 进行了横断面调查。邀请有性接触的男性完成关于漱口水使用的简短问卷，并通过核酸扩增试验检测咽淋病。采用多变量逻辑回归检验漱口水使用与咽淋病检测之间的关系。
在 823 名 MSM 中，咽淋病检出率随年龄组增加而显著下降（≤24 岁，14.5%；25-34 岁，10.7%；≥35 岁，6.0%；ptrend = 0.003）。报告每日使用漱口水的比例随年龄组增加而显著增加（从 10.1%增加到 14.5%，再增加到 19.8%；ptrend = 0.005）。然而，在校正年龄、男性性伴侣数量、人类免疫缺陷病毒状况和漱口水使用类型后，咽淋病检测与每日使用漱口水之间无显著关联。
尽管每日使用漱口水的比例随年龄增加而增加，且咽淋病检出率随年龄增加而降低，但自我报告的漱口水使用与核酸扩增试验检测的咽淋病之间的关联无统计学意义。
