Department of Psychiatry, University of California, San Diego, CA, USA.
Instituto de Psiquiatria, Serviço de Psicologia e Neuropsicologia, Universidade de São Paulo (USP), São Paulo, SP, Brazil.
Braz J Psychiatry. 2017 Aug 31;40(2):128-137. doi: 10.1590/1516-4446-2016-2165. Print 2018 Apr-June.
To explore how a genetically-influenced characteristic (the level of response to alcohol [LR]), ethnicity, and sex relate to environmental and attitudinal characteristics (peer drinking [PEER], drinking to cope [COPE], and alcohol expectancies [EXPECT]) regarding future alcohol-related blackouts (ARBs).
Structural equation models (SEMs) were used to evaluate how baseline variables related to ARB patterns in 462 college students over 55 weeks. Data were extracted from a longitudinal study of heavy drinking and its consequences at a U.S. university.
In the SEM analysis, female sex and Asian ethnicity directly predicted future ARBs (beta weights 0.10 and -0.11, respectively), while all other variables had indirect impacts on ARBs through alcohol quantities (beta weights ~ 0.23 for European American ethnicity and low LR, 0.21 for cannabis use and COPE, and 0.44 for PEER). Alcohol quantities then related to ARBs with beta = 0.44. The SEM explained 23% of the variance.
These data may be useful in identifying college students who are more likely to experience future ARBs over a 1-year period. They enhance our understanding of whether the relationships of predictors to ARBs are direct or mediated through baseline drinking patterns, information that may be useful in prevention strategies for ARBs.
探讨遗传因素（对酒精的反应程度[LR]）、种族和性别如何与环境和态度特征（同伴饮酒[PEER]、饮酒应对[COPE]和酒精期望[EXPECT]）相关，从而影响未来的酒精相关昏迷（ARB）。
采用结构方程模型（SEM）评估了 462 名大学生在 55 周内的基线变量与 ARB 模式的关系。数据来自美国一所大学对重度饮酒及其后果的纵向研究中提取。
在 SEM 分析中，女性性别和亚洲种族直接预测未来的 ARB（β权重分别为 0.10 和-0.11），而其他所有变量都通过酒精量对 ARB 产生间接影响（β权重为 0.23 为欧洲裔美国人种族和低 LR，0.21 为大麻使用和 COPE，0.44 为 PEER）。酒精量与 ARB 的关系为β=0.44。SEM 解释了 23%的方差。
这些数据可能有助于识别在 1 年内更有可能经历未来 ARB 的大学生。它们增强了我们对预测因子与 ARB 之间的关系是直接的还是通过基线饮酒模式介导的理解，这一信息可能对 ARB 的预防策略有用。
