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生姜对降低扁桃体切除术后发病率是否有效?一项前瞻性随机临床试验。

Is Ginger Effective in Reducing Post-tonsillectomy Morbidity? A Prospective Randomised Clinical Trial.

作者信息

Koçak İlker, Yücepur Cemil, Gökler Ozan

机构信息

Department of Otolaryngology, Koç University Hospital, Istanbul, Turkey.

Department of Otolaryngology, Darıca Farabi State Hospital, Kocaeli, Turkey.

出版信息

Clin Exp Otorhinolaryngol. 2018 Mar;11(1):65-70. doi: 10.21053/ceo.2017.00374. Epub 2017 Sep 8.

DOI:10.21053/ceo.2017.00374
PMID:28877566
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5831658/
Abstract

OBJECTIVES

An assessment of the effects of ginger on pain, nausea, vomiting, bleeding, and wound site healing that occur after tonsillectomy.

METHODS

This prospective clinical study was participated by 49 patients aged 18-45 years out of 56 patients that underwent tonsillectomy and regularly attended follow-up visits. The patients were randomly divided into two groups. Group 1 consisted of 23 patients that used ginger capsules and group 2 consisted of 26 patients that did not use ginger capsules in addition to the routine antibiotic and paracetamol treatment following tonsillectomy. The pain, nausea, vomiting, and bleeding scores of patients were assessed on days 1, 4, 7, and 10 by using the visual analogue scale. Similarly, the epithelialization degrees of tonsillar bed were assessed on postoperative days 1, 4, 7, and 10 and regular oral intake times of patients were recorded.

RESULTS

There were no differences between groups in terms of age and sex. On the postoperative days 1, 4, 7, and 10, the pain scores were lower in the group 1 (all <0.001) and there were no differences between the two groups in terms of postoperative nausea, vomiting, and bleeding scores (=0.35 and =0.53). On the postoperative days 7 and 10, epithelialization in the tonsil bed was quicker in the group 1 (=0.041 and =0.026) and the regular oral intake time was earlier in group 1 (<0.001).

CONCLUSION

In this study, ginger relieved pain, accelerated wound site epithelialization, and decreased duration of oral intake following tonsillectomy. It did not result in postoperative bleeding or any other complications. Ginger can be recommended as an adjunct to routine medical treatment for decreasing morbidity following tonsillectomy.

摘要

目的

评估生姜对扁桃体切除术后疼痛、恶心、呕吐、出血及伤口愈合的影响。

方法

本前瞻性临床研究纳入了56例接受扁桃体切除术并定期随访的患者中的49例,年龄在18至45岁之间。患者被随机分为两组。第1组由23例使用生姜胶囊的患者组成,第2组由26例扁桃体切除术后除常规抗生素和扑热息痛治疗外未使用生姜胶囊的患者组成。使用视觉模拟量表在第1、4、7和10天评估患者的疼痛、恶心、呕吐和出血评分。同样,在术后第1、4、7和10天评估扁桃体床的上皮化程度,并记录患者正常经口进食时间。

结果

两组在年龄和性别方面无差异。在术后第1、4、7和10天,第1组的疼痛评分较低(均<0.001),两组在术后恶心、呕吐和出血评分方面无差异(=0.35和=0.53)。在术后第7和10天,第1组扁桃体床的上皮化更快(=0.041和=0.026),且第1组正常经口进食时间更早(<0.001)。

结论

在本研究中,生姜可缓解扁桃体切除术后的疼痛,加速伤口上皮化,并缩短经口进食时间。它不会导致术后出血或任何其他并发症。生姜可作为常规医疗的辅助手段,以降低扁桃体切除术后的发病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fc2/5831658/7863e6e6c00c/ceo-2017-00374f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fc2/5831658/c65abb242bfb/ceo-2017-00374f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fc2/5831658/7863e6e6c00c/ceo-2017-00374f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fc2/5831658/c65abb242bfb/ceo-2017-00374f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fc2/5831658/7863e6e6c00c/ceo-2017-00374f2.jpg

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