Kanwugu Osman Nabayire, Helegbe Gideon Kofi, Aryee Paul Armah, Akontatiba Nathaniel Amigamsa, Ankrah Jacob, Anabire Nsoh Godwin, Anaba Frank, Ahenkora Benjamin
Department of Biochemistry & Molecular Medicine, School of Medicine and Health Sciences, University for Development Studies, P. O. Box TL 1883, Tamale, Ghana.
Department of Community Nutrition, School of Allied Health Sciences, University for Development Studies, P. O. Box TL 1883, Tamale, Ghana.
BMC Res Notes. 2017 Sep 6;10(1):453. doi: 10.1186/s13104-017-2789-0.
The aim of this study was to determine how well the measurements from a glucometer (SD Codefree) correlated with those from a standard auto analyser (BT-3000) using blood samples from diabetic and non-diabetic patients at the Bolgatanga Regional Hospital in Ghana. A cross-sectional study was conducted with a total of 150 randomly selected patients; 100 diabetic patients (4 type 1 and 96 type II) and 50 non diabetic patients. Ante-cubital venous and finger pricked blood samples were obtained from the patients following standard procedures, and blood glucose concentrations were determined using the two methods respectively.
Data generated was entered and analysed using SPSS version 20. The mean glucose concentration for the diabetic patients (n = 100) using the glucometer were not significantly different from that of the auto analyser (10.16 ± 3.708 mmol/L vs. 9.458 ± 3.204 mmol/L, p = 0.154), though the glucometer generally overestimated the glucose concentration. Similarly, readings for non-diabetics were comparable between the two methods (5.286 ± 0.477 mmol/L vs. 5.092 ± 0.525 mmol/L, p = 0.057). The correlation between the two methods was good and highly significant (r = 0.862, p < 0.001) with both methods depicting high sensitivity and specificity in measuring blood glucose levels among diabetics as indicated by the ROC curve.
本研究旨在确定在加纳博尔加坦加地区医院，使用糖尿病患者和非糖尿病患者的血样，血糖仪（SD Codefree）的测量结果与标准自动分析仪（BT - 3000）的测量结果之间的相关性如何。进行了一项横断面研究，共随机选取150名患者；100名糖尿病患者（4名1型和96名2型）和50名非糖尿病患者。按照标准程序从患者的肘前静脉和手指采血，分别使用两种方法测定血糖浓度。
使用SPSS 20版录入并分析生成的数据。糖尿病患者（n = 100）使用血糖仪测得的平均血糖浓度与自动分析仪测得的平均血糖浓度无显著差异（10.16 ± 3.708 mmol/L对9.458 ± 3.204 mmol/L，p = 0.154），不过血糖仪通常会高估血糖浓度。同样，两种方法对非糖尿病患者的读数具有可比性（5.286 ± 0.477 mmol/L对5.092 ± 0.525 mmol/L，p = 0.057）。两种方法之间的相关性良好且高度显著（r = 0.862，p < 0.001），ROC曲线表明两种方法在测量糖尿病患者血糖水平方面均具有高灵敏度和特异性。
