Darcy David G, Yao-Cohen Morgen, Olson Todd R, Downie Sherry A
Department of Surgery, Montefiore Medical Center, 182 East 210th St, Bronx, NY 10467, USA.
Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 14061, USA.
Urol Case Rep. 2017 Sep 1;15:20-22. doi: 10.1016/j.eucr.2017.06.003. eCollection 2017 Nov.
Development of urogenital anatomy in the human fetus is the result of a complex interplay between multiple different tissues. The time course of development is well documented and the morphologic outcomes of insults at various time points during development are predictable. We present a cadaveric case of unilateral agenesis of the left kidney, ureter, bladder hemitrigone, ureteric opening, seminal vesicle, vas deferens, and epididymis. Failure of development of the mesonephric duct early during embryogenesis, likely between the third and fifth week, caused ipsilateral urogenital organ agenesis.
人类胎儿泌尿生殖系统解剖结构的发育是多种不同组织之间复杂相互作用的结果。发育的时间进程有充分记录，并且发育过程中各个时间点损伤的形态学结果是可预测的。我们展示了一例尸体病例，其左肾、输尿管、膀胱半三角区、输尿管开口、精囊、输精管和附睾单侧发育不全。胚胎发生早期，可能在第三至第五周，中肾管发育失败导致同侧泌尿生殖器官发育不全。
