Chi Seong In, Kim Hyun Jeong, Seo Kwang-Suk
Department of Dental Anesthesiology, School of Dentistry, Seoul National University, Seoul, Korea.
J Dent Anesth Pain Med. 2016 Mar;16(1):55-59. doi: 10.17245/jdapm.2016.16.1.55. Epub 2016 Mar 31.
Dental treatment under sedation requires various sedation depths depending on the invasiveness of the procedure and patient drug sensitivity. Inappropriate sedation depth may cause patient discomfort or endangerment. For these reasons, patient-controlled sedation (PCS) pumps are commonly used. Patients are able to control the sedation depths themselves by pushing the demand button after the practitioner sets up the bolus dose and lock-out time. Dexmedetomidine is an α-2 adrenoreceptor agonist with sedative, analgesic, and anxiolytic properties. It has been widely used for sedation for its minimal respiratory depression; however, there are few studies on PCS using dexmedetomidine. This study assessed the applicability of dexmedetomidine to PCS.
镇静状态下的牙科治疗需要根据手术的侵入性和患者的药物敏感性采用不同的镇静深度。不合适的镇静深度可能会导致患者不适或危及患者安全。出于这些原因，患者自控镇静（PCS）泵被普遍使用。在执业医生设定推注剂量和锁定时间后，患者可以通过按下需求按钮自行控制镇静深度。右美托咪定是一种具有镇静、镇痛和抗焦虑特性的α-2肾上腺素能受体激动剂。它因对呼吸的抑制作用极小而被广泛用于镇静；然而，关于使用右美托咪定进行患者自控镇静的研究很少。本研究评估了右美托咪定在患者自控镇静中的适用性。
