Kuk Tae Seong, So Eunsun, Karm Myong-Hwan, Kim Jimin, Chi Seong In, Kim Hyun Jeong, Seo Kwang-Suk, On Sung Woon, Choi Jin-Young
Department of Oral and Maxillofacial Surgery, Seoul National University Dental Hospital, Seoul, Korea.
Department of Dental Anesthesiology, Seoul National University Dental Hospital, Seoul, Korea.
J Dent Anesth Pain Med. 2017 Mar;17(1):71-76. doi: 10.17245/jdapm.2017.17.1.71. Epub 2017 Mar 27.
Drug-induced sleep endoscopy (DISE) is used to identify areas of upper airway obstruction, which occurs when patients with obstructive sleep apnea (OSA) snore. DISE enables effective diagnosis and appropriate treatment of the obstruction site. Among surgical treatment methods for OSA, maxillomandibular advancement surgery (MMA) is performed to move a jaw forward; the surgery has a high success rate for OSA treatment. In DISE, anesthetics such as propofol and midazolam must be administered to induce snoring while the patient is deeply sedated for an accurate diagnosis to be made. When inducing deep sedation in a patient with OSA, airway obstruction may increase, causing oxygen saturation to drop; airway interventions are necessary in such cases. Effective DISE and MMA surgery can be performed by administering propofol through target-controlled infusion while monitoring the bispectral index (BIS).
药物诱导睡眠内镜检查（DISE）用于识别上气道阻塞区域，阻塞性睡眠呼吸暂停（OSA）患者打鼾时会出现这种情况。DISE能够有效诊断阻塞部位并进行适当治疗。在OSA的外科治疗方法中，上颌下颌前移手术（MMA）用于将下颌向前移动；该手术治疗OSA的成功率很高。在DISE中，必须给予丙泊酚和咪达唑仑等麻醉剂，以使患者在深度镇静时打鼾，从而做出准确诊断。在对OSA患者进行深度镇静时，气道阻塞可能会加重，导致血氧饱和度下降；在这种情况下需要进行气道干预。通过在监测脑电双频指数（BIS）的同时通过靶控输注给予丙泊酚，可以进行有效的DISE和MMA手术。
