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生物分子修饰液态金属液滴的操控。

Manipulation of Biomolecule-Modified Liquid-Metal Blobs.

机构信息

Department of Materials and Chemistry, Nanomaterials Research Institute (NMRI), National Institute of Advanced Industrial Science and Technology (AIST), Central 5, 1-1-1 Higashi, Tsukuba, 305-8565, Japan.

出版信息

Angew Chem Int Ed Engl. 2017 Oct 23;56(44):13606-13611. doi: 10.1002/anie.201705996. Epub 2017 Oct 2.

Abstract

Soft and deformable liquid metals (LMs) are building components in various systems related to uncertain and dynamic task environments. Herein we describe the development of a biomolecule-triggered external-manipulation method involving LM conjugates for the construction of future innovative soft robotics operating in physiological environments. Functional soft hybrids composed of a liquid-metal droplet, a thiolated ligand, and proteins were synthesized for the expression of diverse macroscopic commands, such as attachment to cells, binary fusion, and self-propelled movement through molecular recognition and enzymatic reactions. Our technology could be used to create new state-of-the-art soft robots for chemical and biomedical engineering applications.

摘要

软且可变形的液态金属(LMs)是与不确定和动态任务环境相关的各种系统中的构建组件。在此,我们描述了一种基于生物分子触发的外部操作方法的开发,涉及液态金属缀合物,用于构建未来在生理环境中运行的创新软机器人。由液态金属液滴、硫醇配体和蛋白质组成的功能性软杂化材料被合成,用于表达各种宏观命令,如与细胞的附着、二元融合以及通过分子识别和酶反应的自推进运动。我们的技术可用于为化学和生物医学工程应用创建新的最先进的软机器人。

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