Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, North Carolina 27695, USA.
Molecular Imaging Center, Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, P. R. China.
Chem Soc Rev. 2018 Apr 23;47(8):2518-2533. doi: 10.1039/C7CS00309A.
To date, liquid metals have been widely applied in many fields such as electronics, mechanical engineering and energy. In the last decade, with a better understanding of the physicochemical properties such as low viscosity, good fluidity, high thermal/electrical conductivity and good biocompatibility, gallium and gallium-based low-melting-point (near or below physiological temperature) alloys have attracted considerable attention in bio-related applications. This tutorial review introduces the common performances of liquid metals, highlights their featured properties, as well as summarizes various state-of-the-art bio-applications involving carriers for drug delivery, molecular imaging, cancer therapy and biomedical devices. Challenges for the clinical translation of liquid metals are also discussed.
迄今为止，液态金属已广泛应用于电子、机械工程和能源等多个领域。在过去十年中，随着人们对液态金属的物理化学性质（如低粘度、良好的流动性、高热/电导率和良好的生物相容性）有了更好的理解，镓和基于镓的低熔点（接近或低于生理温度）合金在生物相关应用中引起了相当大的关注。本综述介绍了液态金属的常见性能，强调了其特色性质，并总结了涉及药物输送载体、分子成像、癌症治疗和生物医学设备的各种最新生物应用。还讨论了液态金属临床转化的挑战。
