a Nanomedicine Research Laboratory, Department of Pharmaceutics , Indian Institute of Technology (IIT-BHU), Banaras Hindu University , Varanasi , India.
b Department of Pharmaceutics, University Institute of Pharmacy, Faculty of Technology , Pt. Ravishankar Shukla University , Raipur , India.
Artif Cells Nanomed Biotechnol. 2018 Jun;46(4):650-657. doi: 10.1080/21691401.2017.1373284. Epub 2017 Sep 7.
Oral cancer includes cancer of lips, oral cavity and oropharynx. Oral cancer is the sixth most life-threatening disease affecting 65% of population. The delivery of cytotoxic chemotherapeutic anticancer drugs is a challenging task due to unfavorable properties. Both synthetic chemotherapeutic agents and herbal constituents are used in treatment of oral cancer. The purpose of present article is to overcome the limitations through concept of nanotechnology and conjugation approach. Also, it will provide better therapeutic effect and sustain long life of healthy and recovered cells. Moreover, development in this area will raise opportunities for the oncologist, researchers and pharmaceutical scientists. This review summarizes the clinical findings and patents on various oral anticancer drugs for effective pharmacotherapeutics.
口腔癌包括唇癌、口腔癌和口咽癌。口腔癌是影响 65%人群的第六种最具威胁生命的疾病。由于不良性质，细胞毒性化疗抗癌药物的输送是一项具有挑战性的任务。合成化疗药物和草药成分都用于治疗口腔癌。本文的目的是通过纳米技术和结合方法的概念来克服这些限制。此外，它将提供更好的治疗效果，并维持健康和恢复细胞的寿命。此外，这一领域的发展将为肿瘤学家、研究人员和制药科学家提供机会。本文综述了各种口腔抗癌药物的临床发现和专利，以实现有效的药物治疗。
